Ocul Immunol Inflamm. 2013 Jun;21(3):247-50. doi: 10.3109/09273948.2013.766215. Epub 2013 Mar 20.
An inflammation or injury to optic nerve anywhere its pathway by extrinsic lesions causes the optic neuropathy. These lesions are more effective in confined spaces like optic canal, orbital apex. We present a 61 year old woman with optic neuropathy due to lesion in an Onodi cell. In this case patient presented with progressive loss of vision in her right eye within a few days. Computed tomography (CT) revealed mucosal thickening and inflammatory signs in right sphenoid sinus and presence of Onodi cell in that side. Magnetic Resonance Imaging confirmed compression to the optic nevre. Systemic antibioterapy and endoscopic sinus surgery was performed. Postoperatively, the visual acuity and control CT views were better than initial findings. Histopathologic evaluation revealed polyps in Onodi cell. Ophthalmologists should be aware of the Onodi cell pathologies that caused compressive optic neuropathy.
视神经在其通路的任何部位受到外在病变的炎症或损伤都会导致视神经病变。这些病变在外耳道和眶尖等狭小空间内更为有效。我们报告了一例因 Onodi 细胞病变引起的视神经病变的 61 岁女性。在这种情况下,患者在几天内右眼视力逐渐丧失。计算机断层扫描(CT)显示右侧蝶窦黏膜增厚和炎症迹象,以及该侧存在 Onodi 细胞。磁共振成像(MRI)证实视神经受压。给予全身抗生素治疗和鼻内镜鼻窦手术。术后,视力和 CT 检查均优于初始发现。组织病理学评估显示 Onodi 细胞中有息肉。眼科医生应该意识到 Onodi 细胞病变会导致压迫性视神经病变。