Smit Johannes
Department of General Internal Medicine, Radboud University Nijmegen Medical Centre P,O, Box 9101, 6500 HB Nijmegen, The Netherlands.
Thyroid Res. 2013 Mar 14;6 Suppl 1(Suppl 1):S7. doi: 10.1186/1756-6614-6-S1-S7.
Therapy decisions in advanced medullary thyroid carcinoma should be guided by a critical appraisal of the natural disease course (slowly progressive vs. aggressive) and benefits and side effects of therapy. Therapy goals should be distinguished between curative and palliative. Local treatments are mainly palliative and may add to quality of life. The advent of novel systemic therapies opens promising perspectives but its place in the therapeutic arsenal must be further determined.
晚期甲状腺髓样癌的治疗决策应以对疾病自然病程(缓慢进展型与侵袭型)以及治疗的获益和副作用进行批判性评估为指导。治疗目标应区分根治性和姑息性。局部治疗主要是姑息性的,可能会提高生活质量。新型全身治疗方法的出现带来了有前景的治疗前景,但它在治疗手段中的地位仍需进一步确定。