Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. rchaiwar@gmail.com
Jpn J Infect Dis. 2013;66(2):121-5. doi: 10.7883/yoken.66.121.
This retrospective study was conducted among healthcare workers (HCWs) in a tertiary care hospital to (i) determine the incidence of exposure to blood and/or body fluids, (ii) describe the characteristics of such exposures, and (iii) describe management after exposure. There were 1,611 episodes of occupational exposure between January 1, 2005 and December 31, 2010. Of those affected, 1,086 (67.4%) were women. The mean age was 27.6 ± 7.2 years. Nurses (483, 29.9%) were the HCWs most frequently exposed to blood and/or body fluids. The incidence was highest among physicians (11%/year). Percutaneous injury by hollow needles was the most common type of injury (576, 35.8%). Of the 1,611 episodes, 142 (8.8%) comprised HCWs being exposed to human immunodeficiency virus-positive sources. One hundred fifty-one HCWs (9.4%) were exposed to hepatitis B surface (HBs) antigen-positive sources. Sixty-one HCWs had indications for both hepatitis B virus (HBV) vaccine and hepatitis B immunoglobulin; 43 (70.5%) received both. Among the 266 HCWs who had no protective antibody against HBV and were exposed to HBs antigen-negative sources, only 1 (0.4%) received HBV vaccine. These findings suggest that guidelines for post-exposure management among HCWs exposed to HBs antigen-positive sources are not regularly followed. HBV immunization is necessary for all HCWs.
这项回顾性研究在一家三级保健医院的医护人员(HCWs)中进行,旨在:(i)确定接触血液和/或体液的发生率;(ii)描述此类接触的特征;(iii)描述接触后的处理。在 2005 年 1 月 1 日至 2010 年 12 月 31 日期间,发生了 1611 例职业接触事件。受影响者中,有 1086 人(67.4%)为女性。平均年龄为 27.6 ± 7.2 岁。护士(483 人,29.9%)是最常接触血液和/或体液的 HCWs。医生的接触率最高(11%/年)。空心针造成的穿透性损伤是最常见的损伤类型(576 例,35.8%)。在 1611 例事件中,有 142 例(8.8%)是 HCWs 接触到人类免疫缺陷病毒(HIV)阳性源。有 151 名 HCWs(9.4%)接触到乙型肝炎表面(HBs)抗原阳性源。有 61 名 HCWs 有乙型肝炎病毒(HBV)疫苗和乙型肝炎免疫球蛋白的接种指征;其中 43 人(70.5%)同时接种了这两种疫苗。在 266 名没有乙型肝炎表面抗体(抗-HBs)且接触 HBs 抗原阴性源的 HCWs 中,只有 1 人(0.4%)接种了 HBV 疫苗。这些发现表明,接触 HBs 抗原阳性源的 HCWs 接触后处理指南没有得到定期遵循。所有 HCWs 都需要进行 HBV 免疫接种。