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[接受化疗的患者:抑郁与治疗依从性]

[Patients on chemotherapy: depression and adherence to treatment].

作者信息

de Souza Bianca Fresche, Pires Flavia Helena, Dewulf Nathalie de Lourdes Souza, Inocenti Aline, Silva Ana Elisa Bauer de Camargo, Miasso Adriana Inocenti

机构信息

Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brasil.

出版信息

Rev Esc Enferm USP. 2013 Feb;47(1):61-8. doi: 10.1590/s0080-62342013000100008.

DOI:10.1590/s0080-62342013000100008
PMID:23515804
Abstract

This analytical, cross-sectional study applied a quantitative approach to verify the presence of depression and the adherence to a chemotherapy treatment in patients with cancer at the central chemotherapy pharmacy of a university hospital. The sample consisted of 102 patients, and data were collected from October 2010 to May 2011. A structured interview was used to obtain sociodemographic, clinical and therapeutic data; the Morisky Test and Beck Depression Inventory were also applied. The results revealed that 10.8% and 1.9% of participants had moderate and severe depression, respectively. The presence of depression was significantly associated with variables such as income per capita, the number of surgeries, and disease duration. A lack of treatment adherence was identified in 48% of participants. These results indicate the need for health staff training to detect depressive disorders and chemotherapy treatment attrition among patients with cancer.

摘要

这项分析性横断面研究采用定量方法,在一家大学医院的中央化疗药房对癌症患者的抑郁情况及化疗治疗依从性进行验证。样本包括102名患者,数据收集时间为2010年10月至2011年5月。通过结构化访谈获取社会人口学、临床和治疗数据;同时应用了莫利斯基测试和贝克抑郁量表。结果显示,分别有10.8%和1.9%的参与者患有中度和重度抑郁。抑郁的存在与诸如人均收入、手术次数和疾病持续时间等变量显著相关。48%的参与者存在治疗依从性不足的情况。这些结果表明,需要对医护人员进行培训,以检测癌症患者中的抑郁症和化疗治疗中断情况。

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Medicine (Baltimore). 2018 May;97(1S Suppl 1):S38-S45. doi: 10.1097/MD.0000000000009015.

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