Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
Chemistry. 2013 May 10;19(20):6203-8. doi: 10.1002/chem.201300179. Epub 2013 Mar 20.
Congest and conjugate: The application of a sterically congested dipyrromethane in an acid-catalyzed [2+2+2] building-block approach was studied for the first time, resulting in the formation of two stable calix[6]phyrin(1.1.1.1.1.1) diastereomers (see scheme). The calix[n]phyrins were further functionalized at their pentafluorophenyl residues, allowing the first synthesis of a calix[4]phyrin(1.1.1.1) dimer.
首次研究了一个空间位阻的二吡咯甲烷在酸催化的[2+2+2]砌块方法中的应用，得到了两个稳定的杯[6]卟啉（1.1.1.1.1.1）非对映异构体（见方案）。杯[n]卟啉在其五氟苯基残基上进一步官能化，允许首次合成杯[4]卟啉（1.1.1.1）二聚体。
