Cognitive Neuroscience Sector, SISSA, Trieste, Italy.
Cogn Neuropsychol. 2012;29(7-8):531-49. doi: 10.1080/02643294.2013.771773.
We studied the ability of patients with lesions arising from operation for an anterior or posterior (left or right) brain tumour to read a set of words and pronounceable nonwords. In line with previous works, we observed that damage to the left posterior or left anterior cortex can give rise to phonological alexia, where the reading performance of nonwords is affected more than that of words. More surprisingly, similar effects were found in the right posterior group. However, there were significant differences in the error types, for both complex and positional errors, between phonological alexic patients in the three location groups. The findings present difficulties for the position held by theorists of the triangle model that phonological alexia arises from impairments in the language production system or in a general-purpose orthographic-phonological translation system. They also pose new questions about the possible role of the right posterior cortex in letter sequence representation.
我们研究了因左或右脑肿瘤手术而产生病变的患者阅读一组单词和可发音的假词的能力。与之前的工作一致，我们观察到左后或左前皮质损伤会导致语音性失读症，其中假词的阅读表现比单词更受影响。更令人惊讶的是，在右后组中也发现了类似的效果。然而，在三个位置组的语音性失读症患者中，无论是复杂错误还是位置错误，错误类型都存在显著差异。这些发现给三角形模型理论学家所提出的观点带来了困难，即语音性失读症是由于语言产生系统或通用的正字法-语音翻译系统的损伤引起的。它们也对右后皮质在字母序列表示中的可能作用提出了新的问题。
