Moreno Sánchez T, Martín Hervás C, Sola Martínez E, Moreno Rodríguez F
Unidad Clínica de Gestión Diagnóstico por la Imagen, Hospital Juan Ramón Jiménez, Huelva, España; Unidad de Radiología Vascular Intervencionista, Hospital Juan Ramón Jiménez, Huelva, España.
Servicio de Radiodiagnóstico, Hospital Universitario La Paz, Madrid, España.
Radiologia. 2014 Sep-Oct;56(5):420-8. doi: 10.1016/j.rx.2012.12.005. Epub 2013 Mar 19.
The main objectives of this study were to evaluate the sensitivity and specificity of duplex Doppler ultrasonography in the study of hemodialysis peripheral vascular access dysfunction and to analyze the resistance index and flow in the afferent artery.
We prospectively studied 178 patients with 178 peripheral vascular accesses that were dysfunctional in at least three consecutive hemodialysis sessions. Patients underwent duplex Doppler ultrasonography and clinical and laboratory follow-up for three months (provided angiography findings were negative). We calculated the sensitivity, specificity, predictive values, and coefficients of probability. We studied the morphology of the afferent artery, the arteriovenous anastomosis, and the efferent vein, and we measured the resistance index and the flow of the afferent artery, the diameter of the anastomosis, and the flow and peak systolic velocity in the efferent vein.
The final sample consisted of 159 patients. The sensitivity, specificity, positive and negative predictive values, and positive and negative coefficients of probability were 0,98 (95% CI: 0,88-1.00), 0,74 (95% CI: 0,66-0,81), 0,96, 0,82, 3.7, and 0,03, respectively. The resistance index was less than 0,5 in 78.5% of the peripheral vascular accesses with normal function and greater than 0,5 in 86.1% of the dysfunctional peripheral vascular accesses. We found aneurysms in 19 of the native peripheral vascular accesses and pseudoaneurysms in 7 of the prosthetic grafts. Inverted flow was seen in 57 peripheral vascular accesses.
Duplex Doppler ultrasonography is an efficacious method for detecting and characterizing stenosis and thrombosis in peripheral vascular accesses, and it provides information about the morphology and hemodynamics.
本研究的主要目的是评估双功多普勒超声在血液透析外周血管通路功能障碍研究中的敏感性和特异性,并分析传入动脉的阻力指数和血流情况。
我们前瞻性地研究了178例患者的178个外周血管通路,这些通路在至少连续三次血液透析治疗中出现功能障碍。患者接受了双功多普勒超声检查,并进行了为期三个月的临床和实验室随访(前提是血管造影结果为阴性)。我们计算了敏感性、特异性、预测值和概率系数。我们研究了传入动脉、动静脉吻合口和传出静脉的形态,并测量了传入动脉的阻力指数和血流、吻合口直径以及传出静脉的血流和收缩期峰值速度。
最终样本包括159例患者。敏感性、特异性、阳性和阴性预测值以及阳性和阴性概率系数分别为0.98(95%可信区间:0.88 - 1.00)、0.74(95%可信区间:0.66 - 0.81)、0.96、0.82、3.7和0.03。在功能正常的外周血管通路中,78.5%的阻力指数小于0.5,而在功能障碍的外周血管通路中,86.1%的阻力指数大于0.5。我们在19个自体外周血管通路中发现了动脉瘤,在7个人工血管移植物中发现了假性动脉瘤。在57个外周血管通路中观察到了反向血流。
双功多普勒超声是检测和表征外周血管通路狭窄和血栓形成的有效方法,并能提供有关形态和血流动力学的信息。