Takahashi A, Iida H, Kanno I, Ono Y, Uemura K, Shishido F, Inugami A, Murakami M, Sato T, Abe Y
Division of Internal Medicine, Akita Medical Center.
Kaku Igaku. 1990 Mar;27(3):227-35.
Absolute myocardial blood flow (MBF) and myocardial FDG uptake (MFU) in the fasting state were determined in 5 patients who underwent aorto-coronary bypass operation, using O-15 water, F-18 fluoro-deoxyglucose and dynamic PET before and after the operation. In the patent graft region, MBF was increased from 0.59 +/- 0.17 ml/min/g to 0.77 +/- 0.14 ml/min/g (p less than 0.05). Mean MBF was increased from 0.69 +/- 0.22 ml/min/g to 0.83 +/- 0.18 ml/min/g (p less than 0.05). MFU in the fasting state was significantly decreased in high MFU region compared with low MFU region (p less than 0.005). Quantitative evaluation of MBF and MFU before aorto-coronary bypass operation was quite useful to determine adequate indication of the operation.
在5例行主动脉冠状动脉搭桥手术的患者中，于术前和术后使用氧-15水、氟-18氟脱氧葡萄糖及动态正电子发射断层扫描（PET）测定空腹状态下的绝对心肌血流量（MBF）和心肌氟脱氧葡萄糖摄取量（MFU）。在移植血管通畅区域，MBF从0.59±0.17毫升/分钟/克增加至0.77±0.14毫升/分钟/克（p＜0.05）。平均MBF从0.69±0.22毫升/分钟/克增加至0.83±0.18毫升/分钟/克（p＜0.05）。与低MFU区域相比，高MFU区域空腹状态下的MFU显著降低（p＜0.005）。在主动脉冠状动脉搭桥手术前对MBF和MFU进行定量评估对于确定该手术的合适指征非常有用。
