Zhukovskaia S A, Smirnova K M, Nechaeva M E, Zhuravleva V F, Braginskaia P S
Antibiotiki. 1975 Feb;20(2):111-6.
The constants of benzylpenicillin inactivation in acidified fermentation broth filtrates were different in various filtrate batches. Marked inactivation of the antibiotic in the filtrates immediately after their acidification was observed. Possible losses of the antibiotic due to inactivation under conditions of extraction were estimated.
在酸化发酵液滤液中,苄青霉素失活常数在不同批次的滤液中有所不同。在滤液酸化后立即观察到抗生素的显著失活。估计了在提取条件下由于失活导致的抗生素可能损失。