Department of Neurosciences, Division of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, U SA.
J Neurointerv Surg. 2014 Apr 1;6(3):195-9. doi: 10.1136/neurintsurg-2012-010642. Epub 2013 Mar 23.
Dural arteriovenous fistulae (dAVF) of the anterior fossa have a malignant course since they exclusively drain into cortical frontal veins and warrant aggressive treatment. Classically, these lesions have been treated with microsurgical clipping of the fistulous connection. We describe a transvenous approach for Onyx embolization of these lesions that relies on distal venous access using a flexible new-generation guide catheter.
A retrospective review was performed of all patients with an anterior fossa dAVF treated at the Medical University of South Carolina since 2010. Charts, procedural records, angiographic images and follow-up were reviewed. Three patients were identified.
Transfemoral venous access and distal transvenous sinus access was obtained in a retrograde fashion to at least the level of the right transverse sinus. Once a distal guide catheter position was obtained within the venous sinus system, a microcatheter was advanced into the predominant draining anterior frontal cortical vein in preparation for embolization. Onyx 34 embolization was then initiated from this position with the objective of achieving penetration across the vascular shunt.
Our experience demonstrates that transvenous Onyx embolization offers an effective and safe alternative to the classic neurosurgical treatment of anterior fossa dAVF.
颅前窝硬脑膜动静脉瘘 (dAVF) 具有恶性病程,因为它们专门引流至额皮质静脉,需要积极治疗。这些病变传统上采用显微夹闭瘘口的方法治疗。我们描述了一种使用新型柔顺性导引导管经静脉入路用 Onyx 栓塞这些病变的方法,该方法依赖于使用远端静脉入路。
对自 2010 年以来在南卡罗来纳医科大学治疗的所有颅前窝 dAVF 患者进行回顾性研究。对图表、手术记录、血管造影图像和随访进行了回顾。共确定了 3 名患者。
采用逆行方式经股静脉获得远端静脉内入路,至少达到右横窦水平。一旦在静脉窦系统中获得远端导引导管位置,将微导管推进到准备栓塞的主要引流额前皮质静脉中。然后从该位置开始用 Onyx 34 栓塞,目的是使栓塞剂穿透血管分流。
我们的经验表明,经静脉 Onyx 栓塞为颅前窝 dAVF 的经典神经外科治疗提供了一种有效且安全的替代方法。