Ethical, Social and Cultural Program, St Michael's Hospital, Toronto, ON, Canada.
Lancet Infect Dis. 2013 Jun;13(6):540-5. doi: 10.1016/S1473-3099(13)70042-2. Epub 2013 Mar 24.
According to a growing consensus among biomedical researchers, community engagement can improve the ethics and outcomes of clinical trials. Although successful efforts to develop community engagement practices in HIV/AIDS research have been reported, little attention has been given to engagement with the community in tuberculosis research. This article aims to draw attention to some existing community engagement initiatives in tuberculosis research and to resources that might help tuberculosis researchers to establish and implement community engagement programmes for their trials. One of these resources-the good participatory practice guidelines for tuberculosis drug trials-offers a conceptual framework and practical guidance for community engagement in tuberculosis research. To build momentum and to improve community engagement, lessons need to be shared, and formal assessment strategies for community engagement initiatives need to be developed. To build successfully on the promising activities described in this personal view, research funders and sponsors should show leadership in allocation of resources for the implementation and assessment of community engagement programmes in tuberculosis trials.
根据生物医学研究人员越来越多的共识,社区参与可以提高临床试验的伦理和结果。尽管已经报道了在艾滋病毒/艾滋病研究中成功开展社区参与实践的努力,但在结核病研究中与社区的参与却很少受到关注。本文旨在提请注意结核病研究中现有的一些社区参与举措,并提供一些资源,帮助结核病研究人员为其试验建立和实施社区参与方案。这些资源之一是结核病药物试验良好参与实践指南,为结核病研究中的社区参与提供了一个概念框架和实用指南。为了增强动力和改善社区参与,需要分享经验教训,并制定社区参与举措的正式评估策略。为了在本个人观点中描述的有希望的活动基础上取得成功,研究资助者和赞助商应该在为结核病试验中的社区参与方案的实施和评估分配资源方面发挥领导作用。