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荷兰的疫苗接种决定因素。

Vaccine uptake determinants in The Netherlands.

作者信息

van Lier Alies, van de Kassteele Jan, de Hoogh Pieter, Drijfhout Ingrid, de Melker Hester

机构信息

1 Department of Epidemiology and Surveillance (EPI), Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

出版信息

Eur J Public Health. 2014 Apr;24(2):304-9. doi: 10.1093/eurpub/ckt042. Epub 2013 Mar 26.

Abstract

BACKGROUND

Combining existing data on background characteristics with data from immunization registers might give insight into determinants of vaccine uptake, which can help to improve communication strategies and invitation policy of National Immunisation Programmes.

METHODS

The study population consisted of children born in 2005 as registered in the Dutch national immunization register Præventis. A hierarchical logistic regression model was used to quantify associations between individual vaccination status and proxy variables for ethnic background (individual level), socio-economic status (postcode level) and religious objection to vaccination (municipal level).

RESULTS

Most children whose both parents were not born in The Netherlands had a somewhat lower full vaccine uptake, for example, children whose both parents were born in Turkey [odds ratio = 0.7 (0.6-0.8)] or in Morocco [odds ratio = 0.8 (0.7-0.9)]. The partial uptake was also relatively high (3.7-8.0%) compared with children whose both parents were born in The Netherlands (3.1%). Municipalities with higher religious objection to vaccination and postcode areas with lower socio-economic status were also associated with a lower full uptake.

CONCLUSIONS

Despite the high vaccination coverage in The Netherlands, we were able to identify determinants of vaccine uptake by combining existing data sets. This might be an example for other countries. The impact of ethnic background and socio-economic status is not as well known in The Netherlands as the effect of religious objection to vaccination, and deserves more attention. Groups that have a relatively high partial uptake deserve special attention because they do not reject vaccination in general.

摘要

背景

将背景特征的现有数据与免疫登记数据相结合,可能有助于深入了解疫苗接种率的决定因素,这有助于改进国家免疫规划的沟通策略和邀请政策。

方法

研究人群包括在荷兰国家免疫登记系统Præventis中登记的2005年出生的儿童。使用分层逻辑回归模型来量化个体疫苗接种状况与种族背景(个体层面)、社会经济地位(邮政编码层面)和对疫苗接种的宗教反对(市政层面)的代理变量之间的关联。

结果

父母双方均非在荷兰出生的大多数儿童的全程疫苗接种率略低,例如,父母双方均出生在土耳其的儿童[比值比=0.7(0.6-0.8)]或摩洛哥的儿童[比值比=0.8(0.7-0.9)]。与父母双方均在荷兰出生的儿童(3.1%)相比,部分接种率也相对较高(3.7-8.0%)。对疫苗接种宗教反对率较高的市政当局和社会经济地位较低的邮政编码地区也与较低的全程接种率相关。

结论

尽管荷兰的疫苗接种覆盖率很高,但我们通过结合现有数据集能够确定疫苗接种率的决定因素。这可能为其他国家提供一个范例。在荷兰,种族背景和社会经济地位的影响不如对疫苗接种的宗教反对的影响那么为人所知,值得更多关注。部分接种率相对较高的群体值得特别关注,因为他们总体上并不拒绝接种疫苗。

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