Otte J B, de Ville de Goyet J, Alberti D, Balladur P, de Hemptinne B
Department of Pediatric Surgery, University Hospital St-Luc, Brussels, Belgium.
Surgery. 1990 Jun;107(6):605-12.
Extreme scarcity of small pediatric donors makes a search necessary for technical variants to benefit infants and small children from the larger group of potential adolescent and adult donors. Three such technical variants are available for orthotopic transplantation. The reduced-size graft allows a weight ratio between donor and recipient of up to 4 to 6. The segmental graft allows transplantation of segments of livers from adult donors into infants and small children of up to a weight ratio of 8 to 9. The technique of the split liver, whereby one single donor liver is divided in such a way as to obtain two viable grafts for transplantation into two different recipients, is the most recent technical variant used to increase the flexibility of liver replacement and maximize the use of the donor liver pool. We report herein our two first cases of split liver with transplantation in four different recipients, with two long-term survivors. The described technique can also be useful in urgent adult transplantation.
小儿供体极度稀缺，因此有必要探索技术变体，以使婴幼儿能从更大的潜在青少年及成人供体群体中受益。原位移植有三种这样的技术变体。减体积移植可使供体与受体的体重比达到4比6。节段性移植可将成人供体的肝脏节段移植给体重比高达8比9的婴幼儿。劈离式肝移植技术是将一个供体肝脏进行分割，从而获得两个可用于移植给两个不同受体的有活力的移植物，这是最近用于增加肝移植灵活性并最大限度利用供体肝脏库的技术变体。在此，我们报告首例两例劈离式肝移植给四个不同受体的病例，其中有两名长期存活者。所述技术在成人紧急移植中也可能有用。
