Alghamdi Sarah, Omarzai Yumna
Department of Pathology, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
Case Rep Pathol. 2013;2013:672816. doi: 10.1155/2013/672816. Epub 2013 Mar 4.
Malignant melanoma of the gastrointestinal tract is an uncommon neoplasm that could be primary or metastatic. Small intestine represents the most common site for the metastatic melanoma; however, it could be found anywhere in the gastrointestinal tract. Intussusception is a rare cause of intestinal obstruction in adults compared to children. In 90% of the cases, the underlying cause can be found, and in 65% of the cases, intussusception is caused by the neoplastic process. The majority of the neoplasms are benign, and about 15% are malignant. Metastatic melanoma is one of the most common metastatic malignancies to the gastrointestinal tract; however, the premortem diagnosis is rarely made. Here, we report an uncommon clinical presentation of metastatic melanoma causing intussusception in an 80-year-old man. This diagnosis should be considered in a differential diagnosis in any patient who presents with gastrointestinal symptoms and a history of melanoma.
胃肠道恶性黑色素瘤是一种罕见的肿瘤，可为原发性或转移性。小肠是转移性黑色素瘤最常见的部位；然而，它可在胃肠道的任何部位被发现。与儿童相比，肠套叠是成人肠梗阻的罕见原因。在90%的病例中，可以找到潜在病因，65%的病例中，肠套叠由肿瘤性病变引起。大多数肿瘤是良性的，约15%是恶性的。转移性黑色素瘤是胃肠道最常见的转移性恶性肿瘤之一；然而，生前诊断很少做出。在此，我们报告一例80岁男性转移性黑色素瘤导致肠套叠的罕见临床表现。对于任何出现胃肠道症状且有黑色素瘤病史的患者，鉴别诊断时都应考虑这种诊断。
