[The diagnostic and prognostic value of the indices of the colloid-osmotic state of the blood in children with the crush syndrome].

Eighteen infants with compression syndrome (CS) were managed with simultaneous evaluation of changes in the blood colloid osmotic status. The examination findings showed that plasma osmolality is an integral index of endogenous intoxication which objectively reflects the gravity of the general condition of patients and requires adequate correction. The osmolality gap was measured by the difference between the measured and calculated osmolalities; its stable two- or threefold increase was found to be the most unfavourable factor in the disease course and prognosis. It was found that control of osmotic homeostasis in infants with CS is essential to decide that extracorporeal blood clearance techniques be used and to elaborate effective infusion therapy programmes.