• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Evidence for reactivation of human herpesvirus 6 in generalized lymphadenopathy in a patient with drug-induced hypersensitivity syndrome.药物诱导的过敏综合征患者全身淋巴结病中人类疱疹病毒 6 再激活的证据。
J Clin Microbiol. 2013 Jun;51(6):1979-82. doi: 10.1128/JCM.00097-13. Epub 2013 Mar 27.
2
Chronic and recurrent benign lymphadenopathy without constitutional symptoms associated with human herpesvirus-6B reactivation.与人类疱疹病毒 6B 再激活相关的无全身症状的慢性和复发性良性淋巴结病。
Br J Haematol. 2016 Feb;172(4):561-72. doi: 10.1111/bjh.13871. Epub 2015 Dec 18.
3
Pathogenesis from the reactivation of chromosomally integrated human herpesvirus type 6: facts rather than fiction.染色体整合型人类疱疹病毒6型再激活的发病机制：事实而非虚构。
Clin Infect Dis. 2014 Aug 15;59(4):549-51. doi: 10.1093/cid/ciu326. Epub 2014 May 6.
4
Severe encephalitis in a haematopoietic stem cell transplant recipient caused by reactivation of human herpesvirus 6 and 7.造血干细胞移植受者因人类疱疹病毒6型和7型再激活导致的严重脑炎。
J Clin Virol. 2007 Nov;40(3):245-7. doi: 10.1016/j.jcv.2007.08.011. Epub 2007 Oct 2.
5
Drug hypersensitivity syndrome to carbamazepine and human herpes virus 6 infection: case report and literature review.卡马西平所致药物超敏反应综合征与人类疱疹病毒6型感染：病例报告及文献复习
Infection. 2003 Aug;31(4):254-6. doi: 10.1007/s15010-002-3099-5.
6
Association of human herpesvirus 6 reactivation with the flaring and severity of drug-induced hypersensitivity syndrome.人疱疹病毒6型再激活与药物性超敏反应综合征的发作及严重程度的关联
Br J Dermatol. 2007 Nov;157(5):934-40. doi: 10.1111/j.1365-2133.2007.08167.x. Epub 2007 Sep 13.
7
Drug-induced hypersensitivity syndrome due to carbapenem antibiotics.碳青霉烯类抗生素引起的药物超敏反应综合征。
J Dermatol. 2010 Apr;37(4):374-7. doi: 10.1111/j.1346-8138.2010.00820.x.
8
Relevance of Human Herpesvirus 6 Reactivation in Drug Rash With Eosinophilia and Systemic Symptoms.人疱疹病毒6型再激活在药物性皮疹伴嗜酸性粒细胞增多和全身症状中的相关性
JAMA Dermatol. 2024 Jun 1;160(6):687. doi: 10.1001/jamadermatol.2024.0885.
9
Relevance of Human Herpesvirus 6 Reactivation in Drug Rash With Eosinophilia and Systemic Symptoms-Reply.人类疱疹病毒6型再激活在药物性皮疹伴嗜酸性粒细胞增多和全身症状中的相关性——回复
JAMA Dermatol. 2024 Jun 1;160(6):687-688. doi: 10.1001/jamadermatol.2024.0876.
10
[Drug-induced hypersensitivity syndrome].[药物性超敏反应综合征]
Nihon Rinsho. 2012 Aug;70 Suppl 6:498-502.

引用本文的文献

1
Immunopathogenic Insights on Preferential Human Herpesvirus-6 Reactivation in Drug Rash With Eosinophilia and Systemic Symptoms: A Scoping Review.药物性皮疹伴嗜酸性粒细胞增多和全身症状中人类疱疹病毒 6 优先再激活的免疫发病机制研究：范围综述。
J Cutan Med Surg. 2023 Jul-Aug;27(4):388-398. doi: 10.1177/12034754231177590. Epub 2023 May 25.
2
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Focus on the Pathophysiological and Diagnostic Role of Viruses.药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）：聚焦病毒在病理生理和诊断中的作用
Microorganisms. 2023 Jan 30;11(2):346. doi: 10.3390/microorganisms11020346.
3
Chemokines in Severe Cutaneous Adverse Reactions (SCARs).细胞趋化因子在严重皮肤不良反应（SCARs）中的作用。
Biomolecules. 2021 Jun 6;11(6):847. doi: 10.3390/biom11060847.
4
Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS).当前对药物诱导的超敏反应综合征/药物伴嗜酸性粒细胞增多和全身症状（DIHS/DRESS）的免疫发病机制的看法。
Int J Mol Sci. 2021 Feb 21;22(4):2147. doi: 10.3390/ijms22042147.
5
Severe clopidogrel-induced DRESS with eosinophilic pneumonia associated with Epstein-Barr virus reactivation.严重的氯吡格雷诱导的伴有嗜酸性粒细胞性肺炎的药物超敏反应综合征，与EB病毒再激活相关。
Respirol Case Rep. 2020 Feb 20;8(3):e00541. doi: 10.1002/rcr2.541. eCollection 2020 Apr.
6
Lymphoproliferative Syndromes Associated with Human Herpesvirus-6A and Human Herpesvirus-6B.与人类疱疹病毒6A和人类疱疹病毒6B相关的淋巴增殖综合征
Mediterr J Hematol Infect Dis. 2018 May 1;10(1):e2018035. doi: 10.4084/MJHID.2018.035. eCollection 2018.
7
Human herpesvirus 6A infection and immunopathogenesis in humanized Rag2⁻/⁻ γc⁻/⁻ mice.人疱疹病毒 6A 感染与人类 Rag2⁻/⁻ γc⁻/⁻ 小鼠的免疫发病机制。
J Virol. 2013 Nov;87(22):12020-8. doi: 10.1128/JVI.01556-13. Epub 2013 Sep 4.

本文引用的文献

1
Human herpesvirus 6 reactivation in drug-induced hypersensitivity syndrome and DRESS validation score.药物性超敏反应综合征中人类疱疹病毒6的激活及药物性皮疹伴嗜酸性粒细胞增多和系统症状（DRESS）验证评分
Am J Med. 2012 Jul;125(7):e9-10. doi: 10.1016/j.amjmed.2011.10.027.
2
Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management.药物性超敏反应综合征：诊断、发病机制及治疗的最新进展
Chem Immunol Allergy. 2012;97:122-38. doi: 10.1159/000335624. Epub 2012 May 3.
3
Drug hypersensitivity syndrome.药物超敏反应综合征。
Indian J Dermatol Venereol Leprol. 2011 Jan-Feb;77(1):7-15. doi: 10.4103/0378-6323.74964.
4
The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations.基于典型的临床特征和病毒再激活，DRESS综合征的诊断已得到充分确立。
Br J Dermatol. 2007 May;156(5):1083-4. doi: 10.1111/j.1365-2133.2007.07807.x. Epub 2007 Mar 23.
5
Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?伴有全身症状的药物皮肤副作用临床模式的变异性：药物超敏反应伴嗜酸性粒细胞增多和系统症状（DRESS）综合征真的存在吗？
Br J Dermatol. 2007 Mar;156(3):609-11. doi: 10.1111/j.1365-2133.2006.07704.x.
6
Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses.药物性超敏反应综合征（DIHS）：一种由疱疹病毒、抗病毒及抗药物免疫反应之间复杂相互作用引发的反应。
Allergol Int. 2006 Mar;55(1):1-8. doi: 10.2332/allergolint.55.1.
7
Lymphadenopathy induced by anticonvulsant drugs and mimicking clinically pathologically malignant lymphomas.抗惊厥药物所致淋巴结病，临床病理表现酷似恶性淋巴瘤。
Cancer. 1959 Jan-Feb;12(1):164-82. doi: 10.1002/1097-0142(195901/02)12:1<164::aid-cncr2820120122>3.0.co;2-y.
8
Real-time PCR for quantification of human herpesvirus 6 DNA from lymph nodes and saliva.用于定量检测淋巴结和唾液中人类疱疹病毒6型DNA的实时聚合酶链反应
J Clin Microbiol. 2002 Jul;40(7):2445-51. doi: 10.1128/JCM.40.7.2445-2451.2002.
9
Human herpesvirus 6 infection as a risk factor for the development of severe drug-induced hypersensitivity syndrome.人疱疹病毒6型感染是严重药物性超敏反应综合征发生的一个危险因素。
Arch Dermatol. 1998 Sep;134(9):1108-12. doi: 10.1001/archderm.134.9.1108.
10
Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease in patients receiving long-term low-dose methotrexate therapy.接受长期低剂量甲氨蝶呤治疗的患者中的霍奇金病及类似霍奇金病的淋巴组织增生性疾病。
Am J Surg Pathol. 1996 Oct;20(10):1279-87. doi: 10.1097/00000478-199610000-00015.

药物诱导的过敏综合征患者全身淋巴结病中人类疱疹病毒 6 再激活的证据。

Evidence for reactivation of human herpesvirus 6 in generalized lymphadenopathy in a patient with drug-induced hypersensitivity syndrome.

机构信息

Department of Respiratory Medicine, Kyorin University School of Medicine, Tokyo, Japan.

出版信息

J Clin Microbiol. 2013 Jun;51(6):1979-82. doi: 10.1128/JCM.00097-13. Epub 2013 Mar 27.

DOI:10.1128/JCM.00097-13
PMID:23536404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3716082/
Abstract

The present case provides direct evidence of human herpesvirus 6 reactivation in resected lymph node tissue in a patient with drug-induced hypersensitivity syndrome. This case clearly demonstrates that appropriate pathological evaluation of lymphadenopathy for drug-induced hypersensitivity syndrome, which mimics malignant lymphoma in clinical, radiological, and pathological findings, is required.

摘要

本病例提供了药物超敏反应综合征患者切除淋巴结组织中人疱疹病毒 6 再激活的直接证据。本病例清楚地表明，对于在临床、影像学和病理学表现上类似于恶性淋巴瘤的药物超敏反应综合征，需要对淋巴结病进行适当的病理评估。