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呼吸道合胞病毒与利巴韦林治疗:1987年冬季至1988年春季。阿拉斯加安克雷奇普罗维登斯医院74例治疗报告。

Respiratory syncytial virus and ribavirin therapy: winter 1987-spring 1988. A report of 74 cases treated at Providence Hospital, Anchorage, Alaska.

作者信息

Lyon J, Roberts D, Brauner D, Harris J, Pope D

机构信息

Department of Pediatrics, Providence Hospital, Anchorage, Alaska 99508.

出版信息

Alaska Med. 1990 Jan-Mar;32(1):1-5.

PMID:2353740
Abstract

Seventy-four pediatric cases of Respiratory Syncytial Virus lower respiratory tract infection were treated at Providence Hospital, Anchorage, Alaska between September 1, 1987 and April 30, 1988. These patients are described with illustrative case reports. Twenty-one patients were treated with Ribavirin and these patients are further analyzed as a special interest group. A disproportionate number of the Ribavirin treated group were Alaskan Natives. In the discussion we address concerns of possible toxicity of Ribavirin and current recommendations for patient selection for treatment with Ribavirin.

摘要

1987年9月1日至1988年4月30日期间,阿拉斯加安克雷奇普罗维登斯医院对74例呼吸道合胞病毒引起的小儿下呼吸道感染病例进行了治疗。本文通过病例报告对这些患者进行了描述。21例患者接受了利巴韦林治疗,这些患者作为一个特殊兴趣组进行了进一步分析。接受利巴韦林治疗的组中阿拉斯加原住民的比例过高。在讨论中,我们探讨了利巴韦林可能的毒性问题以及目前关于选择利巴韦林治疗患者的建议。

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