Kang Hobin, Darling Cynthia L, Fried Daniel
University of California, San Francisco, San Francisco, CA 94143-0758.
Proc SPIE Int Soc Opt Eng. 2012 Feb 9;8208. doi: 10.1117/12.914636.
Previous remineralization studies employing cross polarization sensitive optical coherence tomography (CP-OCT), have been limited to the repair of artificial enamel-like lesions. In this study we attempted to remineralize existing occlusal lesions on extracted teeth. Lesions were imaged before and after exposure to an acidic remineralization regimen and the integrated reflectivity and lesion depth was calculated. Automated integration routines worked well for assessing the integrated reflectivity for the lesion areas after remineralization. Polarized light microscopy was also used to examine the lesions areas after sectioning the teeth. An acidic remineralization solution was used to remineralize the lesions. The integrated reflectivity significantly increased after exposure to the remineralization solution which suggests that the acidic solution caused additional demineralization as opposed to the desired remineralization.
以往采用交叉极化敏感光学相干断层扫描(CP-OCT)的再矿化研究仅限于人工牙釉质样病变的修复。在本研究中,我们试图使拔除牙齿上现有的咬合病变再矿化。在暴露于酸性再矿化方案之前和之后对病变进行成像,并计算积分反射率和病变深度。自动积分程序在评估再矿化后病变区域的积分反射率方面效果良好。在对牙齿进行切片后,还使用偏光显微镜检查病变区域。使用酸性再矿化溶液使病变再矿化。暴露于再矿化溶液后,积分反射率显著增加,这表明酸性溶液导致了额外的脱矿,而不是预期的再矿化。