Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, United States.
Org Lett. 2013 Apr 19;15(8):1938-41. doi: 10.1021/ol4005905. Epub 2013 Mar 29.
Efficient Alder-ene reactions of various arynes generated directly from bis-1,3-diynes are described. The reactivity of ene donors with different tethers was examined under thermal and metal-catalyzed conditions, which indicates that both the formation of aryne intermediates and their ene reactions are less sensitive to the catalyst than to the structural features of the substrates.
描述了各种由双 1,3-二炔直接生成的芳炔的有效 Alder-ene 反应。在热和金属催化条件下，考察了不同连接基团的烯供体的反应性，结果表明芳炔中间体的形成及其 ene 反应对催化剂的敏感性不如对底物结构特征的敏感性。
