Department of Cardiology, MD Anderson Cancer Center, Houston, TX, USA.
Semin Oncol. 2013 Apr;40(2):199-209. doi: 10.1053/j.seminoncol.2013.01.009.
Infiltrative cardiomyopathies and pericardial involvement frequently complicate the course of malignancy and usually portend a poor outcome. The initial presentation is usually non-specific, and timely diagnosis requires a high index of suspicion on the part of both the oncologist and the consulting cardiologist. The goal of this review was to illustrate three potential infiltrative conditions of the myocardium with associated cardiomyopathies that are encountered in cancer patients: cardiac amyloid, iron overload, and lymphomatous infiltration. We also review the common manifestations of pericardial disease in cancer patients and outline optimal management.
浸润性心肌病和心包受累常使恶性肿瘤的病程复杂化，且通常预示预后不良。首发表现通常无特异性，及时诊断需要肿瘤学家和会诊心脏病专家均高度怀疑。本综述的目的是举例说明在癌症患者中遇到的三种潜在的心肌浸润性疾病及其相关的心肌病：心脏淀粉样变性、铁过载和淋巴瘤浸润。我们还回顾了癌症患者心包疾病的常见表现，并概述了最佳治疗方法。
