Youssef Dima, Raval Brijesh, El-Abbassi Adel, Patel Paras
Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
Tenn Med. 2013 Mar;106(3):37-9.
Blastomycosis rarely presents in pregnancy. Pregnancy is a state of partial immunodeficiency that predisposes to blastomyces infection, especially in endemic areas. Blastomycosis in pregnancy has been reported in a few female patients and their offspring. We are reporting a 32-year-old pregnant patient at 34 weeks of gestation who presented with a lung mass. The cytopathological exam of the biopsy taken by fine needle aspiration showed evidence of Blastomyces organisms. She received Liposomal Amphotericin B and was followed closely until delivery. The placenta was examined and did not show evidence of infection in the fetus. Healthcare professionals in endemic areas such as Tennessee should be aware of blastomycosis in pregnancy.
芽生菌病在孕期很少出现。妊娠是一种部分免疫缺陷状态,易引发芽生菌感染,尤其是在流行地区。少数女性患者及其后代曾有孕期患芽生菌病的报道。我们报告一例34周妊娠的32岁孕妇,其表现为肺部肿块。细针穿刺活检的细胞病理学检查显示有芽生菌的证据。她接受了脂质体两性霉素B治疗,并在分娩前接受密切随访。对胎盘进行检查,未发现胎儿有感染迹象。田纳西州等流行地区的医护人员应了解孕期芽生菌病。