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一种用于治疗两名晚期癌症患者远处淋巴结转移的改良射频消融方法。

A modified radiofrequency ablation approach for treating distant lymph node metastasis in two patients with late-stage cancer.

作者信息

Zou Ru-Hai, Li Qi-Jiong, Qiu Ji-Liang, Liao Ya-Di, Yuan Yun-Fei, Li An-Hua

机构信息

State Key Laboratory of Oncology in South China, Department of Ultrasound, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China.

出版信息

Chin J Cancer. 2013 Oct;32(10):567-70. doi: 10.5732/cjc.012.10190. Epub 2013 Apr 1.

DOI:10.5732/cjc.012.10190
PMID:23544449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3845543/
Abstract

Patients with late-stage cancer commonly have distant lymph node metastasis; however, poor health often contraindicates surgical treatment. Although the quality of life and overall survival for these patients are low, there is neither a consensus nor a guide for treatment. Ablation technique and surrounding tissue damage are two possible reasons for limited study of radiofrequency ablation in patients with superficial distant lymph node metastasis. Here, we report two patients treated successfully with ultrasound-guided radiofrequency ablation for superficial distant lymph node metastasis. In these patients, deionized water was injected to the surrounding tissues of the lymph node to decrease heat injury. Results from these patients suggest that radiofrequency ablation may play an important role in the treatment of patients with distant lymph node metastasis.

摘要

晚期癌症患者通常会出现远处淋巴结转移;然而,身体状况不佳往往使手术治疗成为禁忌。尽管这些患者的生活质量和总生存率较低,但对于治疗既没有共识也没有指南。消融技术和周围组织损伤是浅表远处淋巴结转移患者射频消融研究有限的两个可能原因。在此,我们报告两例经超声引导下射频消融成功治疗浅表远处淋巴结转移的患者。在这些患者中,向淋巴结周围组织注射去离子水以减少热损伤。这些患者的结果表明,射频消融可能在远处淋巴结转移患者的治疗中发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465e/3845543/94f292c74986/cjc-32-10-567-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465e/3845543/32602b9fb718/cjc-32-10-567-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465e/3845543/94f292c74986/cjc-32-10-567-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465e/3845543/32602b9fb718/cjc-32-10-567-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465e/3845543/94f292c74986/cjc-32-10-567-g002.jpg

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Eur J Radiol. 2011 May;78(2):282-6. doi: 10.1016/j.ejrad.2011.01.048. Epub 2011 Feb 5.
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Significance and mechanism of lymph node metastasis in cancer progression.淋巴结转移在癌症进展中的意义和机制。
Cancer Res. 2011 Feb 15;71(4):1214-8. doi: 10.1158/0008-5472.CAN-10-3277. Epub 2011 Jan 6.
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Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: a meta-analysis.
射频消融、经皮酒精和醋酸注射治疗肝细胞癌的临床疗效:荟萃分析。
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VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites.VEGF-C诱导前哨淋巴结淋巴管生成促进肿瘤向远处转移。
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