Zobel G, Kuttnig M, Ring E, Grubbauer H M
Department of Pediatrics, University of Graz, Austria.
Child Nephrol Urol. 1990;10(1):14-7.
Three physiologic scoring systems, the Physiologic Stability Index (PSI), the Pediatric Risk of Mortality (PRISM), the Acute Physiologic Score for Children (APSC), and the Therapeutic Intervention Scoring System (TISS) were applied to 32 critically ill infants and children with acute renal failure or multiple organ system failure undergoing continuous extracorporeal renal support. APSC was developed from the Apache II score. It describes 6 organ systems with 14 variables. PSI describes 7 organ systems with 34 variables, PRISM 5 organ systems with 14 variables. Simultaneously, the TISS was recorded at admission, 24, 48, 96 and 144 h later. All physiologic scores showed significant differences between survivors (S) (n = 18) and nonsurvivors (NS) (n = 14) from admission on. The highest significance was obtained with the APSC (admission score: S: 17.8 +/- 7.4 vs. 27.1 +/- 11.4 NS; p = 0.01; day 4: S: 10.3 +/- 6.1 vs. 26.1 +/- 10.8 NS; p = 0.0001). No significant differences in TISS and in the number of organ system failure were observed during the first 4 days of intensive care.
将三种生理评分系统，即生理稳定性指数（PSI）、儿童死亡风险（PRISM）、儿童急性生理评分（APSC）和治疗干预评分系统（TISS）应用于32例患有急性肾衰竭或多器官系统衰竭并正在接受持续体外肾脏支持的危重症婴幼儿。APSC是从急性生理学与慢性健康状况评分系统II（Apache II）衍生而来。它描述了6个器官系统，包含14个变量。PSI描述了7个器官系统，有34个变量，PRISM描述了5个器官系统，有14个变量。同时，在入院时、24小时、48小时、96小时和144小时后记录TISS。从入院起，所有生理评分在存活者（S）（n = 18）和非存活者（NS）（n = 14）之间均显示出显著差异。APSC的差异最为显著（入院评分：S组为17.8±7.4，NS组为27.1±11.4；p = 0.01；第4天：S组为10.3±6.1，NS组为26.1±10.8；p = 0.0001）。在重症监护的前4天，未观察到TISS和器官系统衰竭数量的显著差异。
