Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, UK; Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, UK.
Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, UK; Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, UK.
J Stroke Cerebrovasc Dis. 2014 Feb;23(2):315-20. doi: 10.1016/j.jstrokecerebrovasdis.2013.03.002. Epub 2013 Mar 30.
Although the association between cerebrovascular and coronary artery disease (CAD) is well known in high-income countries, this association is not well documented in black Africans.
The aim of this study was to document electrocardiographic (ECG) evidence of CAD in stroke cases and controls and to identify other common ECG abnormalities related to known stroke risk factors in a community-based population of incident stroke cases in Tanzania, East Africa.
This was a case-control study. Incident stroke cases were identified by the Tanzanian Stroke Incidence Project. Age- and sex-matched controls were randomly selected from the background population. Electrocardiograms were manually analyzed using the Minnesota Coding System, looking for evidence of previous myocardial infarction (MI), atrial fibrillation (AF) or atrial flutter (AFl), and left ventricular hypertrophy (LVH).
In Hai, there were 93 cases and 241 controls with codable electrocardiograms, and in Dar-es-Salaam, there were 39 cases and 72 controls with codable electrocardiograms. Comparing cases and controls, there was a higher prevalence of MI and AF or AFl (but not LVH) in cases compared with controls.
This is the first published study of ECG assessment of CAD and other stroke risk factors in an incident population of stroke cases in sub-Saharan Africa. It suggests that concomitant CAD in black African stroke cases is more common than previously suggested.
尽管在高收入国家中，脑血管疾病和冠状动脉疾病（CAD）之间存在关联已得到充分证实，但在黑非洲人群中，这种关联尚未得到充分记录。
本研究旨在记录东非坦桑尼亚一个基于社区的首发脑卒中病例人群中，心电图（ECG）对 CAD 的证据，并确定与已知脑卒中危险因素相关的其他常见 ECG 异常。
这是一项病例对照研究。通过坦桑尼亚脑卒中发病项目确定首发脑卒中病例。按照年龄和性别匹配，从背景人群中随机选择对照。使用明尼苏达州编码系统手动分析心电图，寻找既往心肌梗死（MI）、心房颤动（AF）或心房扑动（AFl）和左心室肥厚（LVH）的证据。
在 Hai，有 93 例病例和 241 例可编码心电图的对照，在 Dar-es-Salaam，有 39 例病例和 72 例可编码心电图的对照。与对照组相比，病例组 MI、AF 或 AFl（但不是 LVH）的患病率更高。
这是第一篇在撒哈拉以南非洲首发脑卒中病例人群中进行 ECG 评估 CAD 和其他脑卒中危险因素的发表研究。它表明，在黑非洲脑卒中病例中，同时存在 CAD 的情况比之前认为的更为常见。
