Zhu Wenhui, Tong Yan, Liu Wengang, Wang Yan, Li Chunyan, Zhang Mengxi
Department of Ultrasonography, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Mar;38(3):231-6. doi: 10.3969/j.issn.1672-7347.2013.03.003.
To analyze the characteristics of left ventricular rotation and twist in patients with essential hypertension (EH) of different left ventricular configurations by 3-dimensional speckle tracking echocardiography (3D-STE).
A total of 106 EH patients were divided into 4 groups: a left ventricular normal configuration (LVN) group (n=30), a concentric remodeling (CCR) group (n=31), a concentric hypertrophy (CCH) group (n=29), an eccentric hypertrophy (ECH) group (n=16), and a control group of 30 healthy subjects. The parameters of LVEF, peak basal rotation (Prot-B), peak apical rotation (Prot-A), left ventricular peak apical rotation (LV-rot), and left ventricular peak apical twist (LV-tw) were compared.
The left ventricular mass index in the EH groups, which kept increasing, was higher than that in the normal control group (P<0.05). Compared with the normal control group, LVN and ECH group, the left ventricular posterior wall thickness, interventricular septum at end-diastole, and relative wall thickness significantly increased in the CCH and CCR group (P<0.05). LVEF showed no significant difference among the normal control, LVN, CCR and CCH group (P>0.05), but LVEF was lower in the ECH group than in other groups (P<0.05). Compared with the normal control group, Prot-B, Prot-A, LVrot and LVtw were significantly higher in the LVN, CCR and CCH group (P<0.05), but decreased in the ECH group (P<0.05).
3D-STE can evaluate the left ventricular rotation and twist in EH patients with different configurations, and reflect changes in the left ventricular systolic function in EH of different configurations.
采用三维斑点追踪超声心动图（3D-STE）分析不同左心室构型的原发性高血压（EH）患者左心室旋转和扭转的特征。
106例EH患者分为4组：左心室正常构型（LVN）组（n = 30）、向心性重构（CCR）组（n = 31）、向心性肥厚（CCH）组（n = 29）、离心性肥厚（ECH）组（n = 16），另设30例健康受试者作为对照组。比较左心室射血分数（LVEF）、心底峰值旋转速度（Prot-B）、心尖峰值旋转速度（Prot-A）、左心室峰值心尖旋转（LV-rot）和左心室峰值心尖扭转（LV-tw）等参数。
EH各组左心室质量指数持续升高，高于正常对照组（P<0.05）。与正常对照组、LVN组和ECH组相比，CCH组和CCR组左心室后壁厚度、舒张末期室间隔厚度和相对壁厚度显著增加（P<0.05）。正常对照组、LVN组、CCR组和CCH组之间LVEF差异无统计学意义（P>0.05），但ECH组LVEF低于其他组（P<0.05）。与正常对照组相比，LVN组、CCR组和CCH组的Prot-B、Prot-A、LVrot和LVtw显著升高（P<0.05），而ECH组降低（P<0.05）。
3D-STE可评估不同构型EH患者的左心室旋转和扭转情况，反映不同构型EH患者左心室收缩功能的变化。
