Soares F A, Landell G A, de Freitas M M, de Oliveira J A
Department of Pathology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Gynecol Oncol. 1990 Jul;38(1):141-3. doi: 10.1016/0090-8258(90)90028-j.
Involvement of the pulmonary vessels by tumor emboli has been described from different primary sites of malignancy. A case of pulmonary tumor embolism due to squamous cell carcinoma of the vulva is reported. This form of pulmonary involvement has not previously been described in cases of vulvar carcinoma and it is rare in gynecologic neoplasms. The development of dyspnea with rapid clinical deterioration and fatality associated with multiple pulmonary emboli and histologic signs of pulmonary hypertension is well shown by this case.
肿瘤栓子累及肺血管已在不同原发恶性肿瘤部位有所描述。本文报道了1例因外阴鳞状细胞癌导致的肺肿瘤栓塞病例。这种肺部受累形式此前在外阴癌病例中尚未见报道,在妇科肿瘤中也较为罕见。该病例很好地显示了因多发性肺栓塞以及肺动脉高压的组织学征象而出现的呼吸困难、临床快速恶化及死亡情况。