Wörmann Bernhard, Freund Mathias, Overkamp Friedrich, Ehninger Gerhard
Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Berlin, Deutschland.
Onkologie. 2013;36 Suppl 2:3-8. doi: 10.1159/000348257.
Clinical trials connect basic science with patient care. They form the backbone of evidence-based medicine and clinical guidelines. The unprecedented implementation of new methods in oncology over the past 40 years has only been possible on the basis of multiple well-organized clinical study groups. The continued existence of these study groups in their current multitude is in danger. Far-reaching changes in the legal framework, underfunding, new definitions of patient-related outcome and shifts in the organization of cancer patient care ask for critical reappraisal and new concepts.
临床试验将基础科学与患者护理联系起来。它们构成了循证医学和临床指南的支柱。在过去40年里，肿瘤学领域新方法的前所未有的实施只有在多个组织良好的临床研究小组的基础上才有可能实现。这些研究小组目前数量众多，但其持续存在正面临危险。法律框架的深远变化、资金不足、与患者相关结果的新定义以及癌症患者护理组织的转变都要求进行批判性的重新评估并提出新的概念。
