一名接受抗TNF-α抑制剂治疗的患者患落基山斑疹热。

Rocky Mountain Spotted Fever in a patient treated with anti-TNF-alpha inhibitors.

作者信息

Mays Rana M, Gordon Rachel A, Durham K Celeste, LaPolla Whitney J, Tyring Stephen K

机构信息

Center for Clinical Studies, Webster, TX, USA.

出版信息

Dermatol Online J. 2013 Mar 15;19(3):7.

PMID:23552004

Abstract

Rocky Mountain Spotted Fever (RMSF) is a tick-bourne illness, which can be fatal if unrecognized. We discuss the case of a patient treated with an anti-TNF-alpha inhibitor for rheumatoid arthritis who later developed a generalized erythematous macular eruption accompanied by fever. The clinical findings were suggestive of RMSF, which was later confirmed with serology. Prompt treatment with doxyclycine is recommended for all patients with clinical suspicion of RMSF.

摘要

落基山斑疹热（RMSF）是一种由蜱传播的疾病，如果未被识别，可能会致命。我们讨论了一例类风湿关节炎患者，该患者接受抗TNF-α抑制剂治疗后，出现了全身性红斑性黄斑疹并伴有发热。临床症状提示为落基山斑疹热，后来通过血清学得到证实。对于所有临床怀疑落基山斑疹热的患者，建议立即使用强力霉素进行治疗。