绒毛膜的体积与孕早期脐带的位置有关。
The volume of the chorion villosum is associated with the location of the umbilical cord in the first trimester.
机构信息
Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
出版信息
Prenat Diagn. 2013 Aug;33(8):759-63. doi: 10.1002/pd.4120. Epub 2013 Apr 29.
AIMS
To clarify whether villous placental volumes in cases with low cord insertion (CI) are smaller than those with normal cord insertion.
METHODS
A prospective cohort study was conducted to evaluate the association between location of umbilical CI and placental volume at 11 to 13 weeks' gestation. An ultrasound examination was performed to measure the crown-rump length, the distance between the histological internal cervical os and the CI site, the placental volume, and the uterine arterial blood flow. To standardize the distribution of the ultrasonographic measurements, we transformed data by crown-rump length-weighted linear regression.
RESULTS
Six hundred fifty-nine subjects were analyzed. Scatter plots showed a slightly positive correlation between the z-scores of the distance from the CI site to the internal cervical os and villous placental volume (r = 0.102, p = 0.009) and a negative correlation between the z-scores of the villous placental volume and the uterine arterial pulsatility index (r = -0.165, p < 0.001) as well as the uterine arterial resistance index (r = -0.187, p < 0.001).
CONCLUSION
The placental volume was likely to be smaller in cases with CI located in the lower uterine segment.
目的
明确胎盘绒毛体积是否在脐带插入位置较低（CI）的病例中小于正常 CI 的病例。
方法
进行了一项前瞻性队列研究，以评估脐带 CI 位置与 11 至 13 周妊娠时胎盘体积之间的关系。进行超声检查以测量头臀长、组织学内宫颈口与 CI 部位之间的距离、胎盘体积和子宫动脉血流。为了使超声测量值的分布标准化，我们通过头臀长加权线性回归对数据进行了转换。
结果
分析了 659 例患者。散点图显示，CI 部位到内宫颈口的 z 分数与绒毛胎盘体积之间存在略微正相关（r=0.102，p=0.009），绒毛胎盘体积的 z 分数与子宫动脉搏动指数（r=-0.165，p<0.001）和子宫动脉阻力指数（r=-0.187，p<0.001）呈负相关。
结论
CI 位于子宫下段的病例中胎盘体积可能较小。
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