Yale University School of Medicine, Department of Medicine, Infectious Diseases Section, AIDS Program, 135 College Street (Suite 323), New Haven, CT 06510 2283, USA.
Bull World Health Organ. 2013 Feb 1;91(2):124-9. doi: 10.2471/BLT.12.109132.
In Malaysia, human immunodeficiency virus (HIV) infection is highly concentrated among people who inject opioids. For this reason, the country undertook a three-phase roll-out of a methadone maintenance treatment (MMT) programme. In Phase 3, described in this paper, MMT was implemented within prisons and retention in care was assessed.
After developing standard operating procedures and agreement between its Prisons Department and Ministry of Health, Malaysia established pilot MMT programmes in two prisons in the states of Kelantan (2008) and Selangor (2009) - those with the highest proportions of HIV-infected prisoners. Community-based MMT programmes were also established in Malaysia to integrate treatment activities after prisoners' release.
Having failed to reduce the incidence of HIV infection, in 2005 Malaysia embarked on a harm reduction strategy.
STANDARD OPERATING PROCEDURES WERE MODIFIED TO: (i) escalate the dose of methadone more slowly; (ii) provide ongoing education and training for medical and correctional staff and inmates; (iii) increase the duration of methadone treatment before releasing prisoners; (iv) reinforce linkages with community MMT programmes after prisoners' release; (v) screen for and treat tuberculosis; (vi) escalate the dose of methadone during treatment for HIV infection and tuberculosis; and (vii) optimize the daily oral dose of methadone (> 80 mg) before releasing prisoners.
Prison-based MMT programmes can be effectively implemented but require adequate dosing and measures are needed to improve communication between prison and police authorities, prevent police harassment of MMT clients after their release, and improve systems for tracking release dates.
在马来西亚,艾滋病毒(HIV)感染高度集中在注射类阿片的人群中。因此,该国分三个阶段推出了美沙酮维持治疗(MMT)方案。本文介绍了第三阶段,即在监狱中实施 MMT 并评估患者的保留率。
在制定了标准操作程序并在其监狱部门和卫生部之间达成一致后,马来西亚在两个州(2008 年的吉兰丹州和 2009 年的雪兰莪州)的监狱中设立了试点 MMT 项目,这两个州的 HIV 感染囚犯比例最高。马来西亚还在社区中建立了美沙酮维持治疗方案,以整合囚犯出狱后的治疗活动。
由于未能降低 HIV 感染率,马来西亚于 2005 年开始采取减少伤害战略。
对标准操作程序进行了修改,包括:(i)缓慢增加美沙酮剂量;(ii)为医务人员和囚犯提供持续的教育和培训;(iii)在释放囚犯之前延长美沙酮治疗时间;(iv)在囚犯出狱后加强与社区美沙酮治疗方案的联系;(v)筛查和治疗肺结核;(vi)在治疗 HIV 感染和肺结核期间增加美沙酮剂量;(vii)在释放囚犯之前优化美沙酮的每日口服剂量(>80mg)。
监狱内的 MMT 方案可以有效实施,但需要适当的剂量,还需要采取措施改善监狱和警方之间的沟通,防止警方在囚犯出狱后骚扰美沙酮治疗者,并改善释放日期的跟踪系统。