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本文引用的文献

1
Methadone dose at the time of release from prison significantly influences retention in treatment: implications from a pilot study of HIV-infected prisoners transitioning to the community in Malaysia.出狱时美沙酮剂量显著影响治疗保留率:来自马来西亚艾滋病毒感染者囚犯过渡到社区的试点研究的启示。
Drug Alcohol Depend. 2013 Sep 1;132(1-2):378-82. doi: 10.1016/j.drugalcdep.2013.01.005. Epub 2013 Feb 13.
2
The effectiveness of opioid maintenance treatment in prison settings: a systematic review.监狱环境中阿片类药物维持治疗的效果:系统评价。
Addiction. 2012 Mar;107(3):501-17. doi: 10.1111/j.1360-0443.2011.03676.x.
3
HIV, alcohol dependence, and the criminal justice system: a review and call for evidence-based treatment for released prisoners.HIV、酒精依赖与刑事司法系统:对出狱囚犯的基于证据的治疗的综述与呼吁。
Am J Drug Alcohol Abuse. 2011 Jan;37(1):12-21. doi: 10.3109/00952990.2010.540280. Epub 2010 Dec 21.
4
Better retention of Malaysian opiate dependents treated with high dose methadone in methadone maintenance therapy.美沙酮维持治疗中高剂量美沙酮治疗的马来西亚阿片类依赖者保留率更高。
Harm Reduct J. 2010 Dec 17;7:30. doi: 10.1186/1477-7517-7-30.
5
Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs.治疗感染 HIV 且同时使用毒品的患者的共病(如医学、精神和药物使用)。
Lancet. 2010 Jul 31;376(9738):367-87. doi: 10.1016/S0140-6736(10)60829-X.
6
Prevalence and correlates of community re-entry challenges faced by HIV-infected male prisoners in Malaysia.马来西亚感染艾滋病毒的男性囚犯面临的社区重新融入挑战的患病率及其相关因素。
Int J STD AIDS. 2010 Jun;21(6):416-23. doi: 10.1258/ijsa.2009.009180.
7
Meta-analysis of drug-related deaths soon after release from prison.出狱后不久与药物相关的死亡的荟萃分析。
Addiction. 2010 Sep;105(9):1545-54. doi: 10.1111/j.1360-0443.2010.02990.x. Epub 2010 Jun 23.
8
A randomized clinical trial of methadone maintenance for prisoners: results at 12 months postrelease.一项针对囚犯的美沙酮维持治疗随机临床试验:释放后12个月的结果。
J Subst Abuse Treat. 2009 Oct;37(3):277-85. doi: 10.1016/j.jsat.2009.03.002. Epub 2009 Mar 31.
9
Substitution treatment in Malaysia.马来西亚的替代疗法。
Lancet. 2008 Sep 27;372(9644):1149-50. doi: 10.1016/S0140-6736(08)61479-8.
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Attitudes toward buprenorphine and methadone among opioid-dependent individuals.阿片类药物依赖个体对丁丙诺啡和美沙酮的态度。
Am J Addict. 2008 Sep-Oct;17(5):396-401. doi: 10.1080/10550490802268835.

在马来西亚监狱中实施美沙酮维持治疗。

Implementing methadone maintenance treatment in prisons in Malaysia.

机构信息

Yale University School of Medicine, Department of Medicine, Infectious Diseases Section, AIDS Program, 135 College Street (Suite 323), New Haven, CT 06510 2283, USA.

出版信息

Bull World Health Organ. 2013 Feb 1;91(2):124-9. doi: 10.2471/BLT.12.109132.

DOI:10.2471/BLT.12.109132
PMID:23554524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3605007/
Abstract

PROBLEM

In Malaysia, human immunodeficiency virus (HIV) infection is highly concentrated among people who inject opioids. For this reason, the country undertook a three-phase roll-out of a methadone maintenance treatment (MMT) programme. In Phase 3, described in this paper, MMT was implemented within prisons and retention in care was assessed.

APPROACH

After developing standard operating procedures and agreement between its Prisons Department and Ministry of Health, Malaysia established pilot MMT programmes in two prisons in the states of Kelantan (2008) and Selangor (2009) - those with the highest proportions of HIV-infected prisoners. Community-based MMT programmes were also established in Malaysia to integrate treatment activities after prisoners' release.

LOCAL SETTING

Having failed to reduce the incidence of HIV infection, in 2005 Malaysia embarked on a harm reduction strategy.

RELEVANT CHANGES

STANDARD OPERATING PROCEDURES WERE MODIFIED TO: (i) escalate the dose of methadone more slowly; (ii) provide ongoing education and training for medical and correctional staff and inmates; (iii) increase the duration of methadone treatment before releasing prisoners; (iv) reinforce linkages with community MMT programmes after prisoners' release; (v) screen for and treat tuberculosis; (vi) escalate the dose of methadone during treatment for HIV infection and tuberculosis; and (vii) optimize the daily oral dose of methadone (> 80 mg) before releasing prisoners.

LESSONS LEARNT

Prison-based MMT programmes can be effectively implemented but require adequate dosing and measures are needed to improve communication between prison and police authorities, prevent police harassment of MMT clients after their release, and improve systems for tracking release dates.

摘要

问题

在马来西亚,艾滋病毒(HIV)感染高度集中在注射类阿片的人群中。因此,该国分三个阶段推出了美沙酮维持治疗(MMT)方案。本文介绍了第三阶段,即在监狱中实施 MMT 并评估患者的保留率。

方法

在制定了标准操作程序并在其监狱部门和卫生部之间达成一致后,马来西亚在两个州(2008 年的吉兰丹州和 2009 年的雪兰莪州)的监狱中设立了试点 MMT 项目,这两个州的 HIV 感染囚犯比例最高。马来西亚还在社区中建立了美沙酮维持治疗方案,以整合囚犯出狱后的治疗活动。

当地背景

由于未能降低 HIV 感染率,马来西亚于 2005 年开始采取减少伤害战略。

相关变化

对标准操作程序进行了修改,包括:(i)缓慢增加美沙酮剂量;(ii)为医务人员和囚犯提供持续的教育和培训;(iii)在释放囚犯之前延长美沙酮治疗时间;(iv)在囚犯出狱后加强与社区美沙酮治疗方案的联系;(v)筛查和治疗肺结核;(vi)在治疗 HIV 感染和肺结核期间增加美沙酮剂量;(vii)在释放囚犯之前优化美沙酮的每日口服剂量(>80mg)。

经验教训

监狱内的 MMT 方案可以有效实施,但需要适当的剂量,还需要采取措施改善监狱和警方之间的沟通,防止警方在囚犯出狱后骚扰美沙酮治疗者,并改善释放日期的跟踪系统。