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通过脑磁图结合合成孔径磁测量法对儿童失神癫痫患儿癫痫病灶进行定位

Localization of epileptic foci in Children with childhood absence epilepsy by magnetoencephalography combined with synthetic aperture magnetometry.

作者信息

Hu Xiuxiu, Dong Jingde, Wang Xiaoshan, Wu Ting, Yang Lu, Lu Xiaopeng

机构信息

Department of Geriatric Neurology, Nangjing Brain Hospital, Nanjing, Jiangsu 210029, China;

出版信息

J Biomed Res. 2011 Jul;25(4):259-65. doi: 10.1016/S1674-8301(11)60035-3.

DOI:10.1016/S1674-8301(11)60035-3
PMID:23554699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3597069/
Abstract

This present study was aimed to investigate the localizable diagnostic value of magnetoencephalography (MEG) combined with synthetic aperture magnetometry (SAM) in childhood absence epilepsy (CAE). Thirteen CAE patients underwent MEG detection at resting state and after hyperventilation, and then the epileptic foci were located by SAM. In the thirteen CAE patients, epileptic foci were found in five cases (38.5%), and they were all located in the bilateral frontal lobe, suggesting that the frontal lobe in some CAE patients may serve as the epileptic foci. Our findings indicate that MEG combined with SAM could be of diagnostic value in localizing the epileptic foci in certain CAE patients.

摘要

本研究旨在探讨脑磁图（MEG）联合合成孔径磁ometry（SAM）在儿童失神癫痫（CAE）中的定位诊断价值。13例CAE患者在静息状态和过度换气后接受MEG检测，然后通过SAM定位癫痫灶。在13例CAE患者中，5例（38.5%）发现癫痫灶，均位于双侧额叶，提示部分CAE患者的额叶可能为癫痫灶。我们的研究结果表明，MEG联合SAM对某些CAE患者癫痫灶的定位可能具有诊断价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/74ab573ef98d/jbr-25-04-259-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/e81e3d559377/jbr-25-04-259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/41a034c73239/jbr-25-04-259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/4e5a056173a7/jbr-25-04-259-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/74ab573ef98d/jbr-25-04-259-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/e81e3d559377/jbr-25-04-259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/41a034c73239/jbr-25-04-259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/4e5a056173a7/jbr-25-04-259-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ac3/3597069/74ab573ef98d/jbr-25-04-259-g004.jpg

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本文引用的文献

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Magnetoencephalography adds to the surgical evaluation process.脑磁图增加了手术评估过程。
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