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血管内介入治疗挽救失功血液透析通路的疗效

Outcomes of endovascular intervention for salvage of failing hemodialysis access.

作者信息

Tan Terence Lx, May Kyin K, Robless Peter A, Ho Pei

机构信息

Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre, National University Hospital, Singapore.

出版信息

Ann Vasc Dis. 2011;4(2):87-92. doi: 10.3400/avd.oa.10.00009. Epub 2011 Jun 2.

Abstract

OBJECTIVE

To investigate the effectiveness of endovascular balloon angioplasty to preserve the patency of failing hemodialysis arteriovenous fistulas (AVF) and prosthetic arteriovenous grafts (AVG).

METHODS

Patients on hemodialysis who received endovascular intervention for access problems were retrospectively analyzed. Fistulography was performed on patients who were suspected to have access stenosis and balloon angioplasty performed in the same setting if a stenosis of ≥50% is detected. Patients were followed up for post-operative complications and access restenosis or failure.

RESULTS

42 hemodialysis patients with 44 access sites (29 AVFs, 15 AVGs) required endovascular balloon angioplasty. There were no perioperative complications. Technical success rate was 100%. Median time from initial access creation to first balloon angioplasty was 13 months (2-146 months) for AVFs and 8 months (2-71 months) for AVGs. 19 of 44 patients subsequently developed restenosis. Median time for restenosis or access failure was 11 months (1-18 months) for AVFs and 5 months (1-10 months) for AVGs. Kaplan-Meier analysis for access patency after endovascular intervention showed 72% patency at 6 months and 32% at 12 months.

CONCLUSIONS

Endovascular balloon angioplasty is effective in restoring patency of failing hemodialysis accesses. Recurrence is common, and repeat interventions are required.

摘要

目的

探讨血管内球囊血管成形术对维持失功血液透析动静脉内瘘(AVF)和人工血管动静脉内瘘(AVG)通畅性的有效性。

方法

对因通路问题接受血管内介入治疗的血液透析患者进行回顾性分析。对怀疑有通路狭窄的患者进行瘘管造影,若检测到狭窄≥50%,则在同一情况下进行球囊血管成形术。对患者进行术后并发症及通路再狭窄或失功情况的随访。

结果

42例血液透析患者的44个通路部位(29个AVF,15个AVG)需要进行血管内球囊血管成形术。无围手术期并发症。技术成功率为100%。AVF从最初建立通路到首次球囊血管成形术的中位时间为13个月(2 - 146个月),AVG为8个月(2 - 71个月)。44例患者中有19例随后发生再狭窄。AVF再狭窄或通路失功的中位时间为11个月(1 - 18个月),AVG为5个月(1 - 10个月)。血管内介入治疗后通路通畅性的Kaplan - Meier分析显示,6个月时通畅率为72%,12个月时为32%。

结论

血管内球囊血管成形术对恢复失功血液透析通路的通畅有效。复发常见,需要重复干预。

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