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功能失调的血液透析通路血管成形术的技术成功率与通路通畅率相关吗?

Does Technical Success of Angioplasty in Dysfunctional Hemodialysis Accesses Correlate with Access Patency?

作者信息

Sidhu Arshdeep, Tan Kong T, Noel-Lamy Maxime, Simons Martin E, Rajan Dheeraj K

机构信息

Division of Vascular and Interventional Radiology, Peter Munk Cardiac Center, University Health Network, University of Toronto, 585 University Ave, NCSB 1C-553, Toronto, ON, M5G 2N2, Canada.

Department of Radiology, Providence Hospital and Medical Centers, 16001 W 9 Mile Rd., Southfield, MI, 48075, USA.

出版信息

Cardiovasc Intervent Radiol. 2016 Oct;39(10):1400-6. doi: 10.1007/s00270-016-1401-7. Epub 2016 Jun 22.

Abstract

PURPOSE

To study if <30 % residual stenosis post angioplasty (PTA) correlates with primary access circuit patency, and if any variables predict technical success.

MATERIALS AND METHODS

A prospective observational study was performed between January 2009 and December 2012, wherein 76 patients underwent 154 PTA events in 56 prosthetic grafts (AVG) and 98 autogenous fistulas (AVF). Data collected included patient age, gender, lesion location and laterality, access type and location, number of prior interventions, and transonic flow rates pre- and postintervention. Impact of technical outcome on access patency was assessed. Univariate logistic regression was used to assess the impact of variables on technical success with significant factors assessed with a multiple variable model.

RESULTS

Technical success rates of PTA in AVFs and AVGs were 79.6 and 76.7 %, respectively. Technical failures of PTA were associated with an increased risk of patency loss among circuits with AVFs (p < 0.05), but not with AVGs (p = 0.7). In AVFs, primary access patency rates between technical successes and failures at three and 6 months were 74.4 versus 61.9 % (p = 0.3) and 53.8 versus 23.8 % (p < 0.05), respectively. In AVGs, primary access patency rates between technical successes and failures at three and six months were 72.1 versus 53.9 % (p = 0.5) and 33.6 versus 38.5 % (p = 0.8), respectively. Transonic flow rates did not significantly differ among technically successful or failed outcomes at one or three months.

CONCLUSION

Technical failures of PTA had a significant impact on access patency among AVFs with a trend toward poorer access patency within AVGs.

摘要

目的

研究血管成形术(PTA)后残余狭窄<30%是否与初次通路循环通畅相关,以及是否有变量可预测技术成功。

材料与方法

2009年1月至2012年12月进行了一项前瞻性观察性研究,76例患者在56个人工血管移植物(AVG)和98个自体动静脉内瘘(AVF)中进行了154次PTA手术。收集的数据包括患者年龄、性别、病变位置和侧别、通路类型和位置、既往干预次数以及干预前后的跨音速流速。评估技术结果对通路通畅性的影响。采用单因素逻辑回归评估变量对技术成功的影响,并用多变量模型评估显著因素。

结果

AVF和AVG中PTA的技术成功率分别为79.6%和76.7%。PTA技术失败与AVF通路循环通畅丧失风险增加相关(p<0.05),但与AVG无关(p=0.7)。在AVF中,技术成功组与失败组在3个月和6个月时的初次通路通畅率分别为74.4%对61.9%(p=0.3)和53.8%对23.8%(p<0.05)。在AVG中,技术成功组与失败组在3个月和6个月时的初次通路通畅率分别为72.1%对53.9%(p=0.5)和33.6%对38.5%(p=0.8)。在1个月或3个月时,技术成功或失败的结果之间跨音速流速无显著差异。

结论

PTA技术失败对AVF的通路通畅性有显著影响,AVG的通路通畅性有变差的趋势。

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