Division of Hematology, Chaim Sheba Medical Center Tel Hashomer, Israel and Hematology/Oncology, Cedars-Sinai Medical Center, Los Angeles CA, USA.
Ther Adv Hematol. 2011 Oct;2(5):309-16. doi: 10.1177/2040620711410774.
Myeloid sarcoma is a rare disease that can present as an isolated extramedullary leukemic tumor, concurrently with or at relapse of acute myeloid leukemia. Owing to the rarity of this disorder, most of the literature comprises small retrospective studies and case reports. The aim of this review is to summarize the current published data regarding the clinical presentation, morphological, cytogenetic and molecular features, prognosis and treatment of myeloid sarcoma.
骨髓肉瘤是一种罕见疾病,可表现为孤立性髓外白血病肿瘤,与急性髓细胞白血病同时发生或在其复发时出现。由于这种疾病罕见,大多数文献都是小型回顾性研究和病例报告。本文综述的目的是总结目前关于骨髓肉瘤的临床表现、形态学、细胞遗传学和分子特征、预后和治疗的已发表数据。