Monzen Y, Ajimu A, Hayashi N, Hayashi K
Department of Radiology, Nagasaki University Hospital.
Rinsho Hoshasen. 1990 Apr;35(4):465-70.
54 cases of osteolytic bone tumors were investigated concerning sclerotic change after radiotherapy. Particular attention was paid to the frequency and the appearance time of sclerotic change, and also to the effects of sclerotic change on pathological fracture and prognosis. There was no correlation between the sclerotic change and the frequency of pathological fracture. However, the interval between radiotherapy and pathological fracture tended to be longer in the group with sclerotic change. Sclerotic change after radiotherapy is considered as a sign of good therapeutic local effect and better prognosis.
对54例溶骨性骨肿瘤患者放疗后的硬化改变进行了研究。特别关注了硬化改变的频率和出现时间，以及硬化改变对病理性骨折和预后的影响。硬化改变与病理性骨折的频率之间没有相关性。然而，在出现硬化改变的组中，放疗与病理性骨折之间的间隔往往更长。放疗后的硬化改变被认为是局部治疗效果良好和预后较好的标志。
