Mukae H, Iwamoto M, Takase T, Mori N, Ishino T, Doutsu Y, Kohno S, Yamaguchi K, Hirota M, Hara K
Department of Internal Medicine, Hokusyo Central Hospital, Nagasaki.
Nihon Kyobu Shikkan Gakkai Zasshi. 1990 Feb;28(2):320-9.
Clinical and bacteriological studies were carried out to investigate the isolation of MRSA from sputa and 13 cases with bronchopulmonary infections due to MRSA, during 4 years from 1985 to 1988 at the Hokusyo Central Hospital. The isolation rate of MRSA in Staphylococcus aureus from sputum increased from 0% in 1985 to 51.4% in 1988, and especially from patients in wards for aged people. Most of the MRSA strains were isolated from patients with underlying diseases, or bed sores. The roentgenographic appearances in bronchopulmonary infection patients due to MRSA, showed infiltration and cavitation. Seven out of 13 cases of bronchopulmonary infection due to MRSA died, in spite of therapy with current antibiotics, suggesting poor prognosis of this infection.
1985年至1988年期间，在北海中央医院对痰液中耐甲氧西林金黄色葡萄球菌（MRSA）的分离情况以及13例由MRSA引起的支气管肺部感染病例进行了临床和细菌学研究。痰液中金黄色葡萄球菌的MRSA分离率从1985年的0%上升至1988年的51.4%，特别是在老年病房的患者中。大多数MRSA菌株是从患有基础疾病或褥疮的患者中分离出来的。由MRSA引起的支气管肺部感染患者的影像学表现为浸润和空洞形成。13例由MRSA引起的支气管肺部感染病例中，尽管使用了当前的抗生素进行治疗，仍有7例死亡，提示这种感染的预后较差。
