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二尖瓣手术患者术后6个月随访中健康相关生活质量的比较:一项前瞻性研究。

Comparison of the health related quality of life of patients following mitral valve surgical procedures in the 6-months follow-up: a prospective study.

作者信息

Ay Yasin, Kara Ibrahim, Aydin Cemalettin, Ay Nuray Kahraman, Inan Bekir, Basel Halil, Zeybek Rahmi

机构信息

Department of Cardiovascular Surgery, Bezmialem Vakif University, Adnan Menderes Bulvar 1 (Vatan Cad.), Fatih/Istanbul, Turkey.

出版信息

Ann Thorac Cardiovasc Surg. 2013;19(2):113-9. doi: 10.5761/atcs.oa.12.02234. Epub 2013 Apr 5.

DOI:10.5761/atcs.oa.12.02234
PMID:23558228
Abstract

PURPOSE

The aim of the present study is to evaluate the health-related quality of life of the patients who underwent mitral valve repair (MvRp) and mitral valve replacement (MVR).

METHODS

Within the scope of this prospective study design, 56 patients who had mitral valve operation between the years of 2011-2012 were enrolled in the study. 24 (42.8%) of these patients had MVR while 32 (57.1%) of them had MvRp. The health-related quality of life was evaluated according to the Turkey norms of Short Form 36 Quality-Of-Life Measures (SF-36), which were filled in by the patients before and 6 months after the operation. Moreover, preoperative risk factors affecting the quality of life (age, gender, functional capacity, rhythm, hypertension, diabetes, applied surgical method and echocardiographic results) were investigated for all the patients (n = 56) by using independent sample t test analysis.

RESULTS

When the pre and postoperative changes were compared between the two groups, it was found out that there were no significant difference between the groups in terms of restraints on physical role functioning (PR), and the social role functioning values (SF) (respectively; p = 0.097, p = 0.105). However, in the comparison of pre-/postoperative changes between the groups, the changes in physical functioning (PF), bodily pain (BP), general health (GH), vitality (VT) and restraints on emotional role functioning (RE) and mental health (MH) values were found out to be significantly superior in the MvRp group than in the MVR group (respectively; p <0.01, p <0.05, p <0.01, p <0.01, p <0.05 and p <0.01). It was also confirmed that female gender, atrial fibrillation (AFR), and MVR method negatively affected the physical and mental components (respectively; p = 0.033, p = 0.003, p = 0.015).

CONCLUSION

RESULTS of the SF-36 quality of life measures show that quality of life may be better in patients that have had MvRp. It should be considered that the planned surgical treatment method can affect the patient's quality of life, and this effect can indicate the success of the surgical treatment.

摘要

目的

本研究旨在评估接受二尖瓣修复术(MvRp)和二尖瓣置换术(MVR)患者的健康相关生活质量。

方法

在这项前瞻性研究设计范围内,纳入了2011年至2012年间接受二尖瓣手术的56例患者。其中24例(42.8%)接受了MVR,32例(57.1%)接受了MvRp。根据土耳其版简短健康调查量表(SF-36)的标准,由患者在手术前和术后6个月填写,对健康相关生活质量进行评估。此外,通过独立样本t检验分析,对所有患者(n = 56)术前影响生活质量的危险因素(年龄、性别、功能能力、心律、高血压、糖尿病、所采用的手术方法和超声心动图结果)进行了调查。

结果

比较两组术前和术后的变化时发现,在身体角色功能受限(PR)和社会角色功能值(SF)方面,两组之间无显著差异(分别为:p = 0.097,p = 0.105)。然而,在比较两组术前/术后的变化时,发现MvRp组在身体功能(PF)、身体疼痛(BP)、总体健康(GH)、活力(VT)、情感角色功能受限(RE)和心理健康(MH)值方面的变化明显优于MVR组(分别为:p <0.01,p <0.05,p <0.01,p <0.01,p <0.05和p <0.01)。还证实女性性别、心房颤动(AFR)和MVR方法对身体和心理成分有负面影响(分别为:p = 0.033,p = 0.003,p = 0.015)。

结论

SF-36生活质量测量结果表明,接受MvRp的患者生活质量可能更好。应考虑到计划的手术治疗方法会影响患者的生活质量,且这种影响可表明手术治疗的成功与否。

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