Department of Otolaryngology-Head & Neck Surgery, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, USA.
Am J Otolaryngol. 2013 Sep-Oct;34(5):611-3. doi: 10.1016/j.amjoto.2013.03.003. Epub 2013 Apr 1.
AlloDerm (LifeCell Corporation, Branchburg NJ) is an acellular dermal homograft processed from human cadaveric skin. AlloDerm has been used successfully for soft tissue reconstruction due to its lack of immunogenicity and minimal absorption. In the lip, it has been utilized for aesthetic lip augmentation and as an injectable filler. Description of its usage as an implant in primary lip reconstruction after tumor resection is limited. We describe the case of a 52 year old male with a squamous cell carcinoma of the oral commissure and lower lip. After resection, the defect was reconstructed using implanted AlloDerm for bulk, a buccal mucosal advancement flap, and a cheek rhomboid flap. Lip mobility and oral competence were normal 3 months postoperatively. The reconstruction achieved adequate augmentation without significant resorption. AlloDerm should be considered in primary lip reconstruction after cancer resection.
AlloDerm（LifeCell 公司，新泽西州布兰奇堡）是一种无细胞真皮同种移植物，由人体尸体皮肤加工而成。由于其免疫原性低和吸收最小，AlloDerm 已成功用于软组织重建。在唇部，它已被用于美容唇部增大和注射填充剂。将其作为肿瘤切除后原发性唇重建的植入物的用途描述有限。我们描述了一名 52 岁男性的病例，他患有口腔口角和下唇的鳞状细胞癌。切除后，使用植入的 AlloDerm 进行体积填充、颊黏膜推进瓣和脸颊菱形瓣来重建缺损。术后 3 个月，唇部活动和口腔功能正常。重建实现了足够的增大，没有明显的吸收。AlloDerm 应考虑用于癌症切除后的原发性唇重建。
