Neurosurgical Research Institute, University of Ioannina, Ioannina 45500, Greece.
Eur J Pediatr. 2013 Jun;172(6):733-8. doi: 10.1007/s00431-013-1993-8. Epub 2013 Apr 5.
Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) are among the most common malignancies of childhood. (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) can be employed for accurate staging, treatment planning, and response assessment in pediatric patients with lymphomas, taking advantage of the increased FDG uptake of the malignant cells, secondary to their increased metabolic needs. FDG PET has higher sensitivity than other imaging modalities to detect nodular or diffuse lesions and higher sensitivity than bone marrow biopsy to detect bone marrow infiltration. FDG PET consists of an invaluable imaging modality during evaluation and treatment of pediatric lymphomas.
霍奇金淋巴瘤(HL)和非霍奇金淋巴瘤(NHL)是儿童中最常见的恶性肿瘤之一。18 氟-氟代脱氧葡萄糖(FDG)正电子发射断层扫描(PET)可用于淋巴瘤患儿的准确分期、治疗计划和反应评估,这得益于恶性细胞因代谢需求增加而导致的 FDG 摄取增加。FDG PET 比其他成像方式更敏感,可以检测结节性或弥漫性病变,比骨髓活检更敏感,可以检测骨髓浸润。FDG PET 在评估和治疗儿科淋巴瘤时是一种非常有价值的成像方式。