Yokoyama K, Feldman R G, Sax D S, Salzsider B T, Kucera J
Department of Neurology, Boston University School of Medicine, MA 02118.
Muscle Nerve. 1990 Apr;13(4):314-20. doi: 10.1002/mus.880130406.
Distribution of conduction velocities (DCV) of sensory fibers in sural nerve was investigated in three patients with n-hexane poisoning. Measurements were made at 1-2 months, 4-9 months, and at 11, 23, and 36 months after ending exposure. A sural nerve biopsy was obtained from one of the patients. The results indicated the characteristic changes of n-hexane toxicity: myelinated nerve fiber degeneration and paranodal swelling, resulting in changes in the fiber diameter distribution. The DCV documented these changes. After removal from toxic exposure, varying degrees of recovery were studied clinically and evaluated with nerve conduction parameters. The DCV reflects the pathological changes in nerve in toxic neuropathy due to n-hexane.
对3例正己烷中毒患者的腓肠神经感觉纤维传导速度（DCV）分布进行了研究。在停止接触后的1 - 2个月、4 - 9个月以及11、23和36个月进行了测量。从其中1例患者获取了腓肠神经活检样本。结果显示了正己烷毒性的特征性变化：有髓神经纤维变性和结旁肿胀，导致纤维直径分布改变。DCV记录了这些变化。脱离有毒接触后，对不同程度的恢复情况进行了临床研究，并通过神经传导参数进行评估。DCV反映了正己烷所致中毒性神经病中神经的病理变化。
