Division of Geriatric and Palliative Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
J Geriatr Psychiatry Neurol. 2013 Jun;26(2):78-85. doi: 10.1177/0891988713481264. Epub 2013 Apr 4.
To characterize the prevalence of functional limitations among older adults with cognitive impairment without dementia (CIND).
Secondary data analysis was performed using the Aging, Demographics, and Memory Study data set. A total of 856 individuals aged ≥ 71 years were assigned to 3 diagnostic cognitive categories. A questionnaire was completed by a proxy informant regarding functional limitations for 744 of the 856 respondents.
Of the 744 patients, 263 (13.9%) had dementia, 201 (21.3%) had CIND, and 280 (64.8%) had normal cognition. Informants reported ≥1 instrumental activities of daily living (ADLs) limitation in 45% of the patients with CIND compared to 13% of the patients with normal cognition and 85% of the patients with dementia (P < .001). The ADL impairments among individuals with CIND were primarily attributed to physical health problems (n = 41; 40%).
Many individuals with CIND have impairment in a range of complex and basic daily activities, largely due to physical health problems.
描述认知障碍但无痴呆（CIND）的老年人中功能障碍的流行情况。
使用衰老、人口统计学和记忆研究数据集进行二次数据分析。共有 856 名年龄≥71 岁的个体被分配到 3 个诊断认知类别。由代理人向 856 名受访者中的 744 名完成了一份关于功能障碍的问卷。
在 744 名患者中，263 名（13.9%）患有痴呆症，201 名（21.3%）患有 CIND，280 名（64.8%）认知正常。与认知正常的患者（13%）和痴呆的患者（85%）相比，CIND 患者中有 45%的人报告存在至少 1 项工具性日常生活活动（ADL）受限（P<.001）。CIND 患者的 ADL 损伤主要归因于身体健康问题（n=41；40%）。
许多 CIND 患者在一系列复杂和基本的日常活动中存在障碍，主要是由于身体健康问题。
