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抗高频杰尔比希2抗原抗体(抗-Ge2):交叉配血实验室中的一项真正挑战。

Antibodies against high frequency Gerbich 2 antigen (anti-Ge2): A real challenge in cross matching lab.

作者信息

Singh Ravindra P

机构信息

Department of Transfusion Medicine, PGIMER, Chandigarh, India.

出版信息

Asian J Transfus Sci. 2013 Jan;7(1):88-9. doi: 10.4103/0973-6247.106758.

DOI:10.4103/0973-6247.106758
PMID:23559777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3613676/
Abstract

Transfusion management of patients' alloimmunized against high-prevalence erythrocyte antigens is often problematic in emergency situations. Gerbich (Ge) is very common blood group system and Gerbich-2 (Ge-2) antigen present in high frequency and outside Papua New Guinea population, Ge-2 negative population almost nil. To manage such kind of problems with real emergencies, implementation of rare donor registry program, cryopreservation of red cells of rare donors and biological cross matching to assess significance of these antibodies is warranted.

摘要

对于针对高频率红细胞抗原产生同种免疫的患者,在紧急情况下进行输血管理往往存在问题。杰尔比希(Ge)是非常常见的血型系统,杰尔比希-2(Ge-2)抗原在巴布亚新几内亚人群以外的地区高频存在,几乎不存在Ge-2阴性人群。为了在实际紧急情况下处理这类问题,实施稀有供者登记计划、对稀有供者的红细胞进行冷冻保存以及进行生物学交叉配型以评估这些抗体的意义是必要的。

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本文引用的文献

1
The rare red cell phenotype Gerbich negative in Japanese.
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2
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