Department of Nephrology, Ege University School of Medicine, Izmir, Turkey.
Ren Fail. 2013;35(5):718-20. doi: 10.3109/0886022X.2013.780616. Epub 2013 Apr 8.
The term cardiorenal syndrome (CRS) has been used to define interactions between acute or chronic dysfunction of the heart or kidney. When primary chronic kidney disease contribute to cardiac dysfunction, it is classified as type 4 CRS. Cardiac dilatation, valve regurgitations, and left ventricular dysfunction are observed in end-stage renal failure patients with uremic cardiomyopathy. Because of perioperative risks in these patients, they may not be considered a candidate for kidney transplantation. However, uremic cardiomyopathy can be corrected when volume control is achieved by appropriate dose and duration of ultrafiltration. By presenting two cases with occult hypervolemia in uremic cardiomyopathy whose cardiac functions improved early after kidney transplantation, attention is drawn to the importance of kidney transplantation on cardiac function in such patients primarily and the importance of strict volume control on cardiac function in dialysis patients waiting for kidney transplantation.
心肾综合征（CRS）这一术语用于定义心脏或肾脏急性或慢性功能障碍之间的相互作用。当原发性慢性肾病导致心功能障碍时，将其归类为 4 型 CRS。终末期肾衰竭患者伴有尿毒症性心肌病时，会观察到心脏扩张、瓣膜反流和左心室功能障碍。由于这些患者围手术期风险较高，他们可能不被认为是肾移植的候选者。然而，通过适当的超滤剂量和持续时间实现容量控制，尿毒症性心肌病可以得到纠正。通过介绍两例尿毒症性心肌病中隐匿性高血容量的病例，在肾移植后早期心脏功能得到改善，这引起了人们对肾移植对这类患者心脏功能的重要性的关注，以及对透析患者等待肾移植时严格容量控制对心脏功能的重要性的关注。
