Elliott Robert E, Tanweer Omar, Smith Michael L, Frempong-Boadu Anthony
*Chestmont Neurosurgical, Mainline Health, Newtown Square, PA †Department of Neurosurgery, Bellevue Hospital ‡Department of Neurosurgery, Division of Spinal Neurosurgery, New York University Langone Medical Center, New York, NY.
J Spinal Disord Tech. 2015 Aug;28(7):242-53. doi: 10.1097/BSD.0b013e31828ffc97.
Structured review of literature and application of meta-analysis statistical techniques.
Review published series describing clinical and radiographic outcomes of patients treated with C1 lateral mass screws (C1LMS), specifically analyzing the impact of starting point and bicortical purchase on successful atlantoaxial arthrodesis.
Biomechanical studies suggest posterior arch screws and C1LMS with bicortical purchase are stronger than screws placed within the center of the lateral mass or those with unicortical purchase.
Online databases were searched for English-language articles between 1994 and 2012 describing posterior atlantal instrumentation with C1LMS. Thirty-four studies describing 1247 patients having posterior atlantoaxial fusion with C1LMS met inclusion criteria.
All studies provided class III evidence. Arthrodesis was quite successful regardless of technique (99.0% overall). Meta-analysis and multivariate regression analyses showed that neither posterior arch starting point nor bicortical screw purchase translated into a higher rate of successful arthrodesis. There were no complications from bicortical screw purchase.
The Goel-Harms technique is a very safe and successful technique for achieving atlantoaxial fusion, regardless of minor variations in C1LMS technique. Although biomechanical studies suggest markedly increased rigidity of bicortical and posterior arch C1LMS, the significance of these findings may be minimal in the clinical setting of atlantoaxial fixation and fusion with modern techniques. The decision to use either technique must be made after careful review of the preoperative multiplanar computed tomography imaging, assessment of the unique anatomy of each patient, and the demands of the clinical scenario such as bone quality.
文献的结构化综述及荟萃分析统计技术的应用。
回顾已发表的系列研究,描述接受C1侧块螺钉(C1LMS)治疗患者的临床和影像学结果,特别分析起始点和双皮质固定对寰枢椎成功融合的影响。
生物力学研究表明,双皮质固定的后弓螺钉和C1LMS比置于侧块中心或单皮质固定的螺钉更坚固。
检索在线数据库,查找1994年至2012年间描述使用C1LMS进行寰椎后路内固定的英文文章。34项描述1247例接受C1LMS寰枢椎后路融合术患者的研究符合纳入标准。
所有研究均提供III级证据。无论采用何种技术,融合均相当成功(总体成功率为99.0%)。荟萃分析和多变量回归分析表明,后弓起始点和双皮质螺钉固定均未转化为更高的成功融合率。双皮质螺钉固定未出现并发症。
无论C1LMS技术存在何种细微差异,Goel-Harms技术都是实现寰枢椎融合的非常安全且成功的技术。尽管生物力学研究表明双皮质和后弓C1LMS的刚度显著增加,但在现代技术进行寰枢椎固定和融合的临床环境中,这些发现的意义可能微乎其微。必须在仔细审查术前多平面计算机断层扫描成像、评估每位患者的独特解剖结构以及临床情况(如骨质)的要求后,再决定使用哪种技术。