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肠皮肤瘘:82例病例回顾

Enterocutaneous fistula: a review of 82 cases.

作者信息

Njeze G E, Achebe U J

机构信息

Department of Surgery, University of Nigeria Teaching Hospital, Ituku Ozala, Enugu, Nigeria.

出版信息

Niger J Clin Pract. 2013 Apr-Jun;16(2):174-7. doi: 10.4103/1119-3077.110140.

Abstract

OBJECTIVE

Enterocutaneous fistula is an unpleasant and troublesome complication of abdominal operations. The objective was to review the outcome of treatment of patients treated for enterocutaneous fistula.

MATERIALS AND METHODS

This is a retrospective study of 82 teenage and adult patients, who suffered from enterocutaneous fistula, seen over an 11 year period, in the University of Nigeria Teaching Hospital, Enugu. Patients' charts were reviewed for biodata, etiology of the fistula, volume of the fistula output, and result of treatment. Majority of the fistulas occurred after abdominal operations; many by general practitioners. After treatment for correction of fluid and electrolyte deficits, they were all tried on conservative therapy with enteral nutritional support as the main stay of management. Those, whose fistulas did not close, underwent surgical treatment. Total parenteral nutrition, octreotide, fibrin glue, and wound vacuum assisted closure (VAC) were not used for treating these patients.

RESULTS

Spontaneous healing of fistulas occurred in 26 patients (31.7%), whereas 42 patients out of 50 (84%) healed after definitive operation. Fourteen patients (17%) in this study, died.

CONCLUSION

Proper management of fluid and electrolyte imbalances, enteral nutritional support, control of sepsis and correctly timed surgical therapy, resulted in this good healing rate and acceptable mortality, without the use of parenteral nutrition, biologic fibrin glue injection or VAC. Suggestions are offered about steps that may help in eradicating some of these enterocutaneous fistulas.

摘要

目的

肠皮肤瘘是腹部手术中一种令人不适且棘手的并发症。本研究旨在回顾肠皮肤瘘患者的治疗结果。

材料与方法

这是一项对82例青少年及成年肠皮肤瘘患者的回顾性研究,这些患者于11年间在尼日利亚大学教学医院(位于埃努古)就诊。查阅患者病历,记录其生物数据、瘘管病因、瘘管排出量及治疗结果。大多数瘘管发生于腹部手术后;许多是由全科医生操作导致的。在纠正液体和电解质缺乏后,所有患者均尝试以肠内营养支持作为主要治疗手段的保守治疗。那些瘘管未愈合的患者接受了手术治疗。本研究未使用全胃肠外营养、奥曲肽、纤维蛋白胶及伤口负压封闭引流(VAC)治疗这些患者。

结果

26例患者(31.7%)的瘘管实现了自愈,而在50例接受确定性手术的患者中,有42例(84%)愈合。本研究中有14例患者(17%)死亡。

结论

对液体和电解质失衡进行恰当管理、给予肠内营养支持、控制感染以及适时进行手术治疗,在未使用胃肠外营养、生物纤维蛋白胶注射或VAC的情况下,取得了良好的愈合率和可接受的死亡率。文中还就可能有助于根除部分此类肠皮肤瘘的措施提出了建议。

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