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术后肠造口瘘的手术治疗:不做造口的肠切除加一期吻合术是避免早期复发的安全选择吗?单中心20例报告及文献系统综述

Surgery for post-operative entero-cutaneous fistulas: is bowel resection plus primary anastomosis without stoma a safe option to avoid early recurrence? Report on 20 cases by a single center and systematic review of the literature.

作者信息

Lauro A, Cirocchi R, Cautero N, Dazzi A, Pironi D, Di Matteo F M, Santoro A, Faenza S, Pironi L, Pinna A D

出版信息

G Chir. 2017 Jul-Aug;38(4):185-198. doi: 10.11138/gchir/2017.38.4.185.

DOI:10.11138/gchir/2017.38.4.185
PMID:29182901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5725163/
Abstract

BACKGROUND

A review was performed on entero-cutaneous fistula (ECF) repair and early recurrence, adding our twenty adult patients (65% had multiple fistulas).

METHODS

The search yielded 4.098 articles but only 15 were relevant: 1.217 patients underwent surgery. The interval time between fistula's diagnosis and operative repair was between 3 months and 1 year. A bowel resection with primary anastomosis was performed in 1.048 patients, 192 (18.3%) underwent a covering stoma: 856 patients (81.7%) had a fistula takedown in one procedure.

RESULTS

The patients had 14.3% recurrence and 13.1% mortality rate. In our experience 75% were surgically treated after a period equal or above one year from fistula occurrence: surgery was very demolitive (in 40% remnant small bowel was less than 100 cm). We performed a bowel resection with a hand-sewn anastomosis (95%) without temporary stoma. In-hospital mortality was 0% and at discharge all were back to oral intake with 0% early re-fistulisation.

CONCLUSIONS

Literature supports our experience: ECF takedown could be safely performed after an adequate period of recovery from 3 months to one year from fistula occurrence. In our series primary repair (bowel resection plus reconnection surgery without temporary stoma) avoided an early recurrence without mortality.

摘要

背景

对肠造口瘘(ECF)修复及早期复发情况进行了一项综述,并纳入了我们的20例成年患者(65%有多处瘘管)。

方法

检索到4098篇文章,但仅有15篇相关:1217例患者接受了手术。瘘管诊断至手术修复的间隔时间为3个月至1年。1048例患者进行了肠切除并一期吻合,192例(18.3%)进行了覆盖造口:856例患者(81.7%)在一次手术中进行了瘘管切除。

结果

患者的复发率为14.3%,死亡率为13.1%。根据我们的经验,75%的患者在瘘管出现后1年及以上时间接受了手术治疗:手术创伤很大(40%的患者残余小肠不足100 cm)。我们进行了手工缝合吻合的肠切除(95%),未设置临时造口。住院死亡率为0%,出院时所有患者均恢复经口进食,早期再发瘘管率为0%。

结论

文献支持我们的经验:从瘘管出现起经过3个月至1年的充分恢复期后,可安全地进行ECF切除。在我们的系列研究中,一期修复(肠切除加吻合手术,不设临时造口)避免了早期复发且无死亡病例。

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European Society of Coloproctology consensus on the surgical management of intestinal failure in adults.欧洲结直肠外科学会关于成人肠衰竭外科治疗的共识
Colorectal Dis. 2016 Jun;18(6):535-48. doi: 10.1111/codi.13321.
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Reducing pre-operative length of stay for enterocutaneous fistula repair with a multi-disciplinary approach.采用多学科方法缩短肠造口瘘修复术的术前住院时间。
BMJ Qual Improv Rep. 2015 Jan 16;4(1). doi: 10.1136/bmjquality.u204075.w1773. eCollection 2015.
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