儿童亚临床甲状腺功能减退症
Subclinical hypothyroidism in children.
作者信息
Seshadri Krishna G
机构信息
Department of Endocrinology Diabetes and Metabolism, Sri Ramachandra University, Chennai, India.
出版信息
Indian J Endocrinol Metab. 2012 Dec;16(Suppl 2):S156-8. doi: 10.4103/2230-8210.104028.
Abstract
The prevalence of SH in the pediatric population is < 2%, the caveat being the limited number of studies addressing SCH in the pediatric population. congenital deveolopental anamolies. Mutations in the several proteins are important causes of this condition. Despite the limited data available, SCH in children and adolescents appears to be a benign and remitting disease with a low risk of evolution to OH. It appears that thyroid hormones appear to be functioning well despite elevated TSH. Predictors of progression include, goiter, celiac disease, and positive anti TPO.
摘要
小儿人群中SH的患病率<2%，需要注意的是，针对小儿人群SCH的研究数量有限。先天性发育异常。几种蛋白质的突变是这种疾病的重要病因。尽管可用数据有限，但儿童和青少年的SCH似乎是一种良性且可缓解的疾病，发展为OH的风险较低。尽管促甲状腺激素升高，但甲状腺激素似乎功能良好。进展的预测因素包括甲状腺肿、乳糜泻和抗甲状腺过氧化物酶阳性。
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