肠移植中的机会性病毒感染。

Opportunistic viral infections in intestinal transplantation.

机构信息

Division of Infectious Diseases, Transplant Infectious Diseases Program, University of Nebraska Medical Center, Omaha, NE 68198-5400, USA.

出版信息

Expert Rev Anti Infect Ther. 2013 Apr;11(4):367-81. doi: 10.1586/eri.13.25.

DOI:10.1586/eri.13.25

PMID:23566147

Abstract

Intestinal transplantation (IT) has become a standard treatment for patients with intestinal failure and complications of parenteral nutrition. The pool of intestinal transplant recipients has been slowly growing over the last two decades. Of the 2191 ITs performed between 1 January 1990 and 31 March 2012, 50.5% were children less than 10 years of age. Survival rates at 1, 5 and 10 years have been reported to be 78.5, 58.2 and 47%, respectively. IT restores organ functions, but it is associated with complications, with infections representing the major cause of morbidity and mortality in this population.

摘要

肠移植（IT）已成为治疗肠衰竭和肠外营养并发症患者的标准方法。在过去的二十年中，接受肠移植的患者数量一直在缓慢增长。在 1990 年 1 月 1 日至 2012 年 3 月 31 日期间进行的 2191 例 IT 中，50.5%为年龄小于 10 岁的儿童。据报道，1 年、5 年和 10 年的存活率分别为 78.5%、58.2%和 47%。IT 恢复了器官功能，但它与并发症有关，感染是该人群发病率和死亡率的主要原因。