Bouchoucha S, Gafsi K, Trifa M, Saied W, Ammar C, Nessib M N, Smida M, Ben Ghachem M
Service d'orthopédie de l'enfant et de l'adolescent, hôpital d'enfants de Tunis, 1007 Tunis Jabbari, Bab Saadoun, Tunisie.
Arch Pediatr. 2013 May;20(5):464-9. doi: 10.1016/j.arcped.2013.02.065. Epub 2013 Apr 6.
The aim of this study was to evaluate the results of two antibiotic therapy protocols for osteomyelitis with different durations of intravenous treatment. This was a prospective randomized study of children treated for acute hematogenous osteomyelitis. Patients in group 1 (G1) received 7 days of intravenous antibiotics, whereas patients in group 2 (G2) received 14 days. Treatment was deemed effective if there were no signs of chronic osteomyelitis at the last follow-up. Fifty-three patients were included in the study (G1=27, G2=26). After a mean follow-up of 11.5 months, none of the patients in either group showed signs of chronic osteomyelitis. In conclusion, a shortened treatment of 7 days of intravenous antibiotic therapy is as effective as a longer treatment.
本研究的目的是评估两种不同静脉治疗时长的抗生素治疗方案对骨髓炎的治疗效果。这是一项针对急性血源性骨髓炎患儿的前瞻性随机研究。第1组（G1）患者接受7天静脉抗生素治疗，而第2组（G2）患者接受14天治疗。如果在最后一次随访时没有慢性骨髓炎的迹象，则认为治疗有效。53例患者纳入研究（G1 = 27例，G2 = 26例）。平均随访11.5个月后，两组患者均未出现慢性骨髓炎迹象。总之，7天的静脉抗生素缩短治疗与较长疗程治疗效果相同。
