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区域心肌梗死网络的短期成本效益。

Short term cost effectiveness of a regional myocardial infarction network.

机构信息

Heart Center Rostock, Universitätsklinikum Rostock, Ernst-Heydemann-Str, 6, 18057, Rostock, Germany.

出版信息

Health Econ Rev. 2013 Apr 8;3(1):10. doi: 10.1186/2191-1991-3-10.

DOI:10.1186/2191-1991-3-10
PMID:23566630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3627615/
Abstract

AIMS

Myocardial infarction networks have been shown to improve guideline adherent therapy and outcomes in patients presenting with acute ST-elevation myocardial infarction (STEMI). Our objective was to assess the short term cost effectiveness of a network structure.

METHODS AND RESULTS

Outcome data and reimbursement data for the index hospital stay were gathered in consecutive patients with acute STEMI (n = 536) admitted to any of the hospitals in a 350.000 inhabitant rural network area during the years 2002 (n = 185), 2005 (n = 163) and 2008 (n = 188). Network structure was established between 2002 and 2005 aiming for identical treatment of all acute STEMI patients during 24 h/7d a week with primary angioplasty. Patient baseline characteristics in the different years were quite comparable. From 2002 to 2005 regional hospital mortality in STEMI patients decreased from 16% to 9%. Lower mortality under network conditions was confirmed in 2008. Reimbursement data of different years were standardized to exclude effects not induced by the network. The mean initial costs per saved live during the index stay were €7727 with a 95%-confidence interval of €-3.500 to €36.700 (referenced to the German reimbursement in 2005).

CONCLUSION

The short term cost effectiveness of a myocardial infarction network organisation is within well accepted boundaries under conditions of the German reimbursement system.

摘要

目的

心肌梗死网络已被证明可以改善急性 ST 段抬高型心肌梗死(STEMI)患者的指南依从性治疗和结局。我们的目的是评估网络结构的短期成本效益。

方法和结果

连续收集了 2002 年(n=185)、2005 年(n=163)和 2008 年(n=188)在一个拥有 35 万居民的农村网络区域内任何一家医院就诊的急性 STEMI 患者的住院结局数据和指数住院期间的报销数据。2002 年至 2005 年期间建立了网络结构,目标是在每周 24 小时/7 天内对所有急性 STEMI 患者进行相同的治疗,采用直接经皮冠状动脉介入治疗。不同年份的患者基线特征相当可比。从 2002 年到 2005 年,STEMI 患者的区域医院死亡率从 16%下降到 9%。在 2008 年,网络条件下死亡率较低得到了证实。不同年份的报销数据已标准化,以排除非网络因素的影响。指数住院期间每挽救一条生命的平均初始成本为 7727 欧元,95%置信区间为-3500 至 36700 欧元(参考 2005 年德国报销标准)。

结论

在德国报销制度的条件下,心肌梗死网络组织的短期成本效益在可接受的范围内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58b5/3627615/70cbfa0ea089/2191-1991-3-10-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58b5/3627615/70cbfa0ea089/2191-1991-3-10-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58b5/3627615/70cbfa0ea089/2191-1991-3-10-1.jpg

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本文引用的文献

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2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.2013年美国心脏病学会基金会/美国心脏协会ST段抬高型心肌梗死管理指南:执行摘要:美国心脏病学会基金会/美国心脏协会实践指南工作组报告
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The cost-effectiveness of primary prophylactic implantable defibrillator therapy in patients with ischaemic or non-ischaemic heart disease: a European analysis.
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Eur Heart J. 2013 Jan;34(3):211-9. doi: 10.1093/eurheartj/ehs090. Epub 2012 May 14.
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Abortion of myocardial infarction by primary angioplasty mainly depends on preprocedural TIMI flow.直接经皮冠状动脉成形术治疗心肌梗死时,梗死心肌的早期再灌注主要依赖于术前 TIMI 血流分级。
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